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Popis: Golgi auto-antigen; probably involved in maintaining cis-Golgi structure.
Katalogové číslo: BOSSBS-8155R-A350
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Golgi auto-antigen; probably involved in maintaining cis-Golgi structure.
Katalogové číslo: BOSSBS-8155R-FITC
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Golgi auto-antigen; probably involved in maintaining cis-Golgi structure.
Katalogové číslo: BOSSBS-8155R-A680
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Pipette, Repetitive
Katalogové číslo: 613-6939
Měrná jednotka: 1 * 1 KS
Dodavatel: Brand


Popis: Ro autoantigens are of clinical significance because directed against them are found in most patients with primary Sjqgren syndrome, subacute cutaneous lupus erythematosus (SLE), neonatal lupus erythematosus, ANA-negative lupus erythematosus, and systemic lupus erythematosus-like disease secondary to homozygous C2 or C4 complement deficiency (1). Ro/SSA is a ribonucleoprotein that binds to auto in 35 to 50% of patients with SLE and in up to 97% of patients with Sjqgren syndrome (2). The Ro/SSA particle consists of a single immunoreactive protein noncovalently bound with one of four small RNA molecules (2). Most anti-Ro/SSA-positive sera detect not only the main protein, but also a smaller Ro/SSA protein (2). The genes which encode the smaller and larger proteins map to human chromosomes 11p15.5 and 1q31, respectively (3?). La/SSB is an autoimmune RNA-binding protein that plays a role in the transcription of RNA polymerase III was originally defined by its reactivity with auto from patients with Sjé°ƒren syndrome and SLE (6).
Katalogové číslo: BOSSBS-7116R-CY5
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
Katalogové číslo: BOSSBS-4308R-HRP
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
Katalogové číslo: BOSSBS-4308R-A350
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
Katalogové číslo: BOSSBS-4308R-CY3
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
Katalogové číslo: BOSSBS-8680R-A647
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
Katalogové číslo: BOSSBS-8680R-CY5.5
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: ANXA9 may act as a low affinity receptor for acetylcholine and is expressed in the stratified squamous skin epithelium, but not in epithelia of other types (at protein level). ANXA9 is one of the target molecules recognized by auto in patients with pemphigus vulgaris, a rare, autoimmune skin disease in which epidermal blisters occur as the result of the loss of cell-cell adhesion.
Katalogové číslo: BOSSBS-5916R
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
Katalogové číslo: BOSSBS-8680R-FITC
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Amphiphysin is associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff man syndrome who were also affected by breast cancer are positive for auto against this protein. Alternate splicing of this gene results in two transcript variants (Amphiphysin 1 and Amphiphysin 2) encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined.
Katalogové číslo: BOSSBS-2409R-A488
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: ANXA9 may act as a low affinity receptor for acetylcholine and is expressed in the stratified squamous skin epithelium, but not in epithelia of other types (at protein level). ANXA9 is one of the target molecules recognized by auto in patients with pemphigus vulgaris, a rare, autoimmune skin disease in which epidermal blisters occur as the result of the loss of cell-cell adhesion.
Katalogové číslo: BOSSBS-5916R-A555
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase.
Katalogové číslo: BOSSBS-1980R-CY3
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase.
Katalogové číslo: BOSSBS-1980R-CY5.5
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


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