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Popis: Anti-Aspartate Aminotransferase+FABP-1 Rabbit Monoclonal Antibody [clone: EPR12145]
Katalogové číslo: ABCAAB170950-1ML
Měrná jednotka: 1 * 1 mL
Dodavatel: Abcam

New Product


Popis: Pepstatin is a potent inhibitor of various aspartic proteases, including cathepsin D, renin, pepsin, bacterial aspartic proteases and HIV proteases. Soluble in DMSO or methanol.
Katalogové číslo: 786-052
Měrná jednotka: 1 * 25 mg
Dodavatel: G-Biosciences


Popis: The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s disease, epilepsy and ischemic neuronal cell death. Increased membrane surface expression of the NR1 subunit of the receptor has been associated with synaptic plasticity. There are a number of different splice variants of the NR1. Differential splicing of three exons in the NR1 subunit generates up to eight NR1 splice variants and 7 of these have been identified in cDNA libraries. These exons encode a 21 amino acid N-terminal domain (N1) and adjacent sequences in the C-terminus (C1 and C2). Splicing out the C2 cassette eliminates the first stop codon and produces a new reading frame that generates a new sequence of 22 amino acids (C2'). Considerable attention has been focused on the distribution and expression of these splice variants that may affect the functional properties and regulation of the NMDAR.
Katalogové číslo: PRSIXPS-2020
Měrná jednotka: 1 * 25 µG
Dodavatel: ProSci Inc.


Popis: Anti-Glutamate/Aspartate Transporter 2 Mouse Monoclonal Antibody [clone: 10H26]
Katalogové číslo: USBIG4003-91A
Měrná jednotka: 1 * 100 µG
Dodavatel: US Biological


Popis: Anti-Aspartate Aminotransferase Rabbit Polyclonal Antibody
Katalogové číslo: ABCAAB230424-50
Měrná jednotka: 1 * 50 µl
Dodavatel: Abcam


Popis: The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s disease, epilepsy and ischemic neuronal cell death. Increased membrane surface expression of the NR1 subunit of the receptor has been associated with synaptic plasticity. There are a number of different splice variants of the NR1. Differential splicing of three exons in the NR1 subunit generates up to eight NR1 splice variants and 7 of these have been identified in cDNA libraries. These exons encode a 21 amino acid N-terminal domain (N1) and adjacent sequences in the C-terminus (C1 and C2). Splicing out the C2 cassette eliminates the first stop codon and produces a new reading frame that generates a new sequence of 22 amino acids (C2'). Considerable attention has been focused on the distribution and expression of these splice variants that may affect the functional properties and regulation of the NMDAR.
Katalogové číslo: PRSIXPS-2021
Měrná jednotka: 1 * 25 µG
Dodavatel: ProSci Inc.


Popis: The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s disease, epilepsy and ischemic neuronal cell death. Increased membrane surface expression of the NR1 subunit of the receptor has been associated with synaptic plasticity. There are a number of different splice variants of the NR1. Differential splicing of three exons in the NR1 subunit generates up to eight NR1 splice variants and 7 of these have been identified in cDNA libraries. These exons encode a 21 amino acid N-terminal domain (N1) and adjacent sequences in the C-terminus (C1 and C2). Splicing out the C2 cassette eliminates the first stop codon and produces a new reading frame that generates a new sequence of 22 amino acids (C2'). Considerable attention has been focused on the distribution and expression of these splice variants that may affect the functional properties and regulation of the NMDAR.
Katalogové číslo: PRSIXPS-2022
Měrná jednotka: 1 * 25 µG
Dodavatel: ProSci Inc.


Popis: Anti-Aspartate beta hydroxylase Rabbit Monoclonal Antibody [clone: EPR10351]
Katalogové číslo: ABCAAB172475-100
Měrná jednotka: 1 * 100 µl
Dodavatel: Abcam


Popis: Anti-Aspartate Aminotransferase+FABP-1 Rabbit Monoclonal Antibody [clone: EPR12145] (HRP)
Katalogové číslo: ABCAAB201765-100
Měrná jednotka: 1 * 100 µl
Dodavatel: Abcam


Popis: Anti-Aspartate Aminotransferase Rabbit Monoclonal Antibody [clone: EPR20781-274]
Katalogové číslo: ABCAAB259691-100
Měrná jednotka: 1 * 100 µG
Dodavatel: Abcam


Popis: Anti-Aspartate Aminotransferase Rabbit Monoclonal Antibody [clone: EPR20781-22]
Katalogové číslo: ABCAAB259695-100
Měrná jednotka: 1 * 100 µG
Dodavatel: Abcam


Popis: Anti-Aspartate Aminotransferase+FABP-1 Rabbit Monoclonal Antibody [clone: EPR12145] (Alexa Fluor® 594)
Katalogové číslo: ABCAAB310525-100UL
Měrná jednotka: 1 * 100 µl
Dodavatel: Abcam


Popis: Anti-Aspartate Aminotransferase+FABP-1 Rabbit Monoclonal Antibody [clone: EPR12145] (Alexa Fluor® 568)
Katalogové číslo: ABCAAB312532-100UL
Měrná jednotka: 1 * 100 µl
Dodavatel: Abcam


Popis: This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis.
Katalogové číslo: PRSI56-642
Měrná jednotka: 1 * 400 µl
Dodavatel: ProSci Inc.

New Product


Popis: Anti-Aspartate Aminotransferase+FABP-1 Rabbit Monoclonal Antibody [clone: EPR12145] (Alexa Fluor® 488)
Katalogové číslo: ABCAAB309749-100UL
Měrná jednotka: 1 * 100 µl
Dodavatel: Abcam


Popis: Anti-Aspartate beta hydroxylase Rabbit Monoclonal Antibody [clone: EPR10351]
Katalogové číslo: ABCAAB249694-100
Měrná jednotka: 1 * 100 µG
Dodavatel: Abcam


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