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Image Unavailable-BOSSBS-2623R-A680

Anti-IL-22 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-2623R-A680)
Dodavatel: Bioss
Popis: Cytokine that contributes to the inflammatory response in vivo.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-2623R-CY7

Anti-IL22 Rabbit Polyclonal Antibody (Cy7®)

Katalogové číslo: (BOSSBS-2623R-CY7)
Dodavatel: Bioss
Popis: Cytokine that contributes to the inflammatory response in vivo.
Měrná jednotka: 1 * 100 µl
Image Unavailable-ENZOBMLFA0180050

Palmitoylethanolamide ≥98% (by TLC)

Katalogové číslo: (ENZOBMLFA0180050)
Dodavatel: ENZO LIFE SCIENCES
Popis: Endogenous cannabinoid. Weak ligand of CB1 (Ki=23.8µM) and CB2 (Ki=13.9µM) receptor. Inhibits fatty acid amide hydrolase (FAAH) (IC50=5.1µM). Immunosuppressant, anti-inflammatory, anti-nociceptive and anti-convulsant in vivo. The exact mode of action has not yet been revealed. It has been suggested that PEA: i) binds to a yet to be discovered cannabinoid receptor similar to CB2; ii) administered in vivo elicits the synthesis of endogenous agonists of CB2; iii) acts as an "entourage" compound by enhancing the activity and/or by influencing the turnover of endogenous agonists of CB2, possibly but not uniquely, by inhibiting their degradation.
Měrná jednotka: 1 * 50 mg

New Product


Product Image-ENZOALX430141M010

BPMO ≥99% (by 1H-NMR), high purity

Dodavatel: ENZO LIFE SCIENCES
Popis: Nitrone spin trap for the specific <i>in vivo</i> or <i>in vitro</i> detection of short-lived superoxide, hydroxyl and thiyl radicals.

New Product

Image Unavailable-ENZOBMLEI2400100

(R)-(-)-Deprenyl hydrochloride ≥98% (by HPLC)

Katalogové číslo: (ENZOBMLEI2400100)
Dodavatel: ENZO LIFE SCIENCES
Popis: Deprenyl inhibits apoptosis and displays neuroprotective effects in a variety of in vitro and in vivo systems. In vivo it rescues nigral dopaminergic neurons after systemic MPTP treatment. In vitro it rescues PC12 cells from apoptotic cell death induced by trophic withdrawal. The putative target responsible for the anti-apoptotic effects is glyceraldehyde-3-phosphate dehydrogenase. Deprenyl also inhibits monoamine oxidase-B, which is not involved in its anti-apoptotic mechanism. Parkinson’s disease therapeutic.
Měrná jednotka: 1 * 100 mg

New Product


Image Unavailable-ENZOBMLPI1470025

PKSI-527 ≥95% (by HPLC)

Dodavatel: ENZO LIFE SCIENCES
Popis: Highly selective plasma kallikrein inhibitor (Ki = 0.81 µM). Can be used for affinity purification of kalikrein. Suppresses collagen-induced arthritis in a mouse model. Synergizes with NO donors producing antithrombotic effects ex vivo.

New Product

Image Unavailable-ENZOALX270459M005

PQ401 ≥98% (by HPLC and UV method)

Katalogové číslo: (ENZOALX270459M005)
Dodavatel: ENZO LIFE SCIENCES
Popis: Potent inhibitor of insulin-like growth factor I receptor (IGF-IR) signalling and breast cancer cell growth in culture and in vivo.
Měrná jednotka: 1 * 5 mg

New Product


Image Unavailable-40-9919-U100

Anti-CD178 (Fas ligand) Mouse Antibody (In Vivo Ready™) [clone: NOK-1]

Katalogové číslo: (40-9919-U100)
Dodavatel: Tonbo Biosciences
Popis: The NOK-1 antibody reacts with human CD178 (Fas ligand) in both membrane bound and soluble forms. Fas ligand is a 40 kDa transmembrane glycoprotein, a member of the TNF family, and is expressed by activated T and NK cells, neutrophils, and monocytes. Interactions between CD178 (Fas ligand) and CD95 (Fas) induce a program of apoptosis and play a key role in immune regulation and homeostasis. The extracellular domain of human CD178 can be cleaved from the surface by matrix metalloproteinases (MMPs) resulting in a 26 kDa soluble protein.
Měrná jednotka: 1 * 100 µG
Image Unavailable-ENZOBMLPI1290002

Gliotoxin (from Gladiocladium fimbriatum) ≥97% (by HPLC, TLC)

Dodavatel: ENZO LIFE SCIENCES
Popis: Immunomodulating mycotoxin which acts by blocking membrane thiol groups. Inhibits the chymotrypsin-like activity of the 20S proteasome in a non-competitive manner. Causes apoptotic cell death in macrophages and thymocytes. Induces Ca2+ release from intact rat liver mitochondria. Inhibits the activation of transcription factor NF-κB in response to a variety of stimuli in T and B cells. Displays anti-inflammatory activity in vivo. Antioxidant. Inhibitor of farnesyltransferase and geranylgeranyltransferase I. A negative control analog is available. Displays anti-tumor activity against breast cancer in vivo.

New Product

Image Unavailable-ENZOALX746255C100

Duo-iODN (inhibitory ODN) (synthetic) endotoxin-free

Katalogové číslo: (ENZOALX746255C100)
Dodavatel: ENZO LIFE SCIENCES
Popis: Inhibitory iODN oligodeoxynucleotide with phosphorothioate backbone. Sequence of an inhibitory ODN for in vivo use in rodents (50-150µg per injection): prototype class I that potently inhibits TLR9 and TLR7 signaling.
Měrná jednotka: 1 * 100 µG

New Product


Image Unavailable-CAYM71740-10

Rosiglitazone ≥98%

Dodavatel: Cayman Chemical
Popis: Thiazolidinediones (TZDs) are a group of structurally related peroxisome proliferator-activated receptor γ (PPARγ) agonists with antidiabetic actions <italic>in vivo</italic>. Rosiglitazone is a prototypical TZD and has served as a reference compound for this class. Rosiglitazone is a potent and selective PPARγ ligand. It binds to the PPARγ ligand-binding domain with a Kd of 43 nM. It activates luciferase-based expression constructs PPARγ1 and PPARγ2 with EC<sub>50</sub> values of approximately 30 nM and 100 nM, respectively. Rosiglitazone is active <italic>in vivo</italic> as an antidiabetic agent in the <italic>ob/ob</italic> mouse model, and has been used as an oral hypoglycemic agent in the treatment of Type II diabetes in humans for many years.

Image Unavailable-BOSSBS-1755R-HRP

Anti-EGFL7 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Katalogové číslo: (BOSSBS-1755R-HRP)
Dodavatel: Bioss
Popis: Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cell adhesion to the extracellular matrix and angiogenesis.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1303R-CY3

Anti-SFRP1 Rabbit Polyclonal Antibody (Cy3®)

Katalogové číslo: (BOSSBS-1303R-CY3)
Dodavatel: Bioss
Popis: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-1303R-A555

Anti-SFRP1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalogové číslo: (BOSSBS-1303R-A555)
Dodavatel: Bioss
Popis: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-2623R-CY3

Anti-IL22 Rabbit Polyclonal Antibody (Cy3®)

Katalogové číslo: (BOSSBS-2623R-CY3)
Dodavatel: Bioss
Popis: Cytokine that contributes to the inflammatory response in vivo.
Měrná jednotka: 1 * 100 µl
Image Unavailable-ENZOBMLEI3400050

BIBB-515 ≥98% (by TLC)

Katalogové číslo: (ENZOBMLEI3400050)
Dodavatel: ENZO LIFE SCIENCES
Popis: BIBB 515 is a potent and selective inhibitor of 2,3-oxidosqualene cyclase (OSC) in vivo. BIBB 515 inhibits LDL production in both normolipemic and hyperlipemic hamsters and may represent a novel approach for the development of lipid lowering drugs.
Měrná jednotka: 1 * 50 mg

New Product


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Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Daná chemikálie je regulována dle platné legislativy a bude vyžadováno vyplnění formuláře. Jeho včasným vyplněním uspíšíte dodání produktu.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Tento produkt je zablokován vaší organizací. Kontaktujte své nákupní oddělení pro více informací.
Původní produkt již není k dispozici. Zobrazen je náhradní produkt.
Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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