Hledali jste: Antibiotické+Testy

Katalogové číslo: (BOSSBS-13618R-CY7)

Dodavatel: Bioss

Popis: A variety of morphological and molecular changes are required for mature spermatozoa formation. These steps are temporally guided by the transcription and translation of several testis-specific genes. SPANX (sperm protein associated with the nucleus, X-linked) family members are sperm- and testis-specific proteins containing between 97-103 amino acids, whose genes form a cluster on chromosome X. Sharing a high level of sequence similarity, SPANX-A, -B, -C, -D and -E localize to both cytoplasm and nucleus where they are associated with nuclear craters. SPANX-B (Sperm protein associated with the nucleus on the X chromosome B/F) is a 103 amino acid protein that is detected in round and elongating spermatids.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-15401R-A750)

Dodavatel: Bioss

Popis: H2BFWT (H2B histone family member W testis-specific) is a 175 amino acid nuclear membrane histone that belongs to the histone H2B family. In contrast to most H2B histones, H2BFWT does not contain the conserved C-terminal residue involved in monoubiquitination, but is structurally indistinguishable from conventional H2B histones. Also varying from other H2B histones, H2BFWT does not participate in the recruitment of chromosome condensation factors or in the assembly of mitotic chromsomes. Expressed in testis, H2BFWT is present in sperm cells and may be essential to telomere function.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-7930R-FITC)

Dodavatel: Bioss

Popis: Tissue specificity:Widely expressed. Most abundant in testis, skeletal muscle, and heart.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-6231R-CY3)

Dodavatel: Bioss

Popis: MAGEF1 is a member of the MAGE (melanoma antigen gene) superfamily.Most known members of the MAGE superfamily are expressed in tumors, testis and fetal tissues, which has been described as a cancer/testis or "CT" expression pattern. MAGEF1, however, is expressed in all adult and fetal tissues tested, as well as in many tumor types including ovarian, breast, cervical, melanoma and leukemia. The coding region of MAGE-F1 is contained within a single exon and includes a microsatellite repeat. Several MAGE genes are ubiquitously expressed suggesting a role for MAGE encoded proteins in normal cell physiology.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-6231R-A350)

Dodavatel: Bioss

Popis: MAGEF1 is a member of the MAGE (melanoma antigen gene) superfamily.Most known members of the MAGE superfamily are expressed in tumors, testis and fetal tissues, which has been described as a cancer/testis or "CT" expression pattern. MAGEF1, however, is expressed in all adult and fetal tissues tested, as well as in many tumor types including ovarian, breast, cervical, melanoma and leukemia. The coding region of MAGE-F1 is contained within a single exon and includes a microsatellite repeat. Several MAGE genes are ubiquitously expressed suggesting a role for MAGE encoded proteins in normal cell physiology.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-13618R-CY3)

Dodavatel: Bioss

Popis: A variety of morphological and molecular changes are required for mature spermatozoa formation. These steps are temporally guided by the transcription and translation of several testis-specific genes. SPANX (sperm protein associated with the nucleus, X-linked) family members are sperm- and testis-specific proteins containing between 97-103 amino acids, whose genes form a cluster on chromosome X. Sharing a high level of sequence similarity, SPANX-A, -B, -C, -D and -E localize to both cytoplasm and nucleus where they are associated with nuclear craters. SPANX-B (Sperm protein associated with the nucleus on the X chromosome B/F) is a 103 amino acid protein that is detected in round and elongating spermatids.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-7758R)

Dodavatel: Bioss

Popis: Tissue specificity: Highly expressed in lung, muscle, testis, brain, heart, liver, leukocyte and spleen. Lower expression in ovary, prostate and kidney.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-7930R-A488)

Dodavatel: Bioss

Popis: Tissue specificity:Widely expressed. Most abundant in testis, skeletal muscle, and heart.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-7930R-A647)

Dodavatel: Bioss

Popis: Tissue specificity:Widely expressed. Most abundant in testis, skeletal muscle, and heart.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-1217R)

Dodavatel: Bioss

Popis: TSARG3 may be involved in inhibiting testis spermatogenesis apoptosis.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-9116R-A350)

Dodavatel: Bioss

Popis: Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements. BAGE, also known as B melanoma antigen 1 or cancer/testis antigen 2.1, is a 43 amino acid member of the BAGE family. Generally, BAGE proteins are not expressed in normal tissues, except in testis, but are expressed highly in melanomas, bladder carcinomas, head and neck squamous cell carcinomas, and lung and breast cancer carcinomas. BAGE proteins are not expressed in renal, colorectal and prostatic carcinomas, leukemias and lymphomas.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-7681R)

Dodavatel: Bioss

Popis: May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.Tissue specificity: Ubiquitously expressed with higher levels in testis.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-8193R)

Dodavatel: Bioss

Popis: Tumor-associated antigen.Tissue specificity:Expressed in testis, placenta and skin. Expressed at lower level in mammary gland and stomach.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-9719R)

Dodavatel: Bioss

Popis: The PDE4A8 is a testis germ cell-specific PDE4A variant. There are two PDE4A variants identified in rat testis (PDE4A8 and an un-characterized 76 kDa PDE4A protein). Spermatogenesis is accompanied by expression of a varied repertoire of PDE4 enzymes at different stages of cell differentiation that presumably perform specialized functions. Confocal microscopic examination revealed the presence of PDE4A8 in primary and secondary spermatids but not in mature spermatozoa. PDE4A8 inhibition results in increased apoptosis of the germ cells accompanied with reduction in the number of mature spermatozoa.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-9719R-CY5)

Dodavatel: Bioss

Popis: The PDE4A8 is a testis germ cell-specific PDE4A variant. There are two PDE4A variants identified in rat testis (PDE4A8 and an un-characterized 76 kDa PDE4A protein). Spermatogenesis is accompanied by expression of a varied repertoire of PDE4 enzymes at different stages of cell differentiation that presumably perform specialized functions. Confocal microscopic examination revealed the presence of PDE4A8 in primary and secondary spermatids but not in mature spermatozoa. PDE4A8 inhibition results in increased apoptosis of the germ cells accompanied with reduction in the number of mature spermatozoa.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-11309R-A680)

Dodavatel: Bioss

Popis: The testis spermatocyte apoptosis-related gene 2 protein (TSARG2, also designated spermatogenesis associated-4 or SPATA4) is involved in spermatogenesis. TSARG2 is specifically expressed in spermatogonia and spermatocytes of the seminiferous tubules, and it localizes to the nucleus. The predicted molecular weight of TSARG2 ranges depending on the species. TSARG2 is significantly upregulated in cryptorchidism and therefore, is a testis-specific apoptosis candidate oncogene.

Měrná jednotka: 1 * 100 µl

Akce