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Image Unavailable-BOSSBS-6231R-CY7

Anti-MAGEF1 Rabbit Polyclonal Antibody (Cy7®)

Katalogové číslo: (BOSSBS-6231R-CY7)
Dodavatel: Bioss
Popis: MAGEF1 is a member of the MAGE (melanoma antigen gene) superfamily.Most known members of the MAGE superfamily are expressed in tumors, testis and fetal tissues, which has been described as a cancer/testis or "CT" expression pattern. MAGEF1, however, is expressed in all adult and fetal tissues tested, as well as in many tumor types including ovarian, breast, cervical, melanoma and leukemia. The coding region of MAGE-F1 is contained within a single exon and includes a microsatellite repeat. Several MAGE genes are ubiquitously expressed suggesting a role for MAGE encoded proteins in normal cell physiology.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13618R-CY7

Anti-SPANXB1 Rabbit Polyclonal Antibody (Cy7®)

Katalogové číslo: (BOSSBS-13618R-CY7)
Dodavatel: Bioss
Popis: A variety of morphological and molecular changes are required for mature spermatozoa formation. These steps are temporally guided by the transcription and translation of several testis-specific genes. SPANX (sperm protein associated with the nucleus, X-linked) family members are sperm- and testis-specific proteins containing between 97-103 amino acids, whose genes form a cluster on chromosome X. Sharing a high level of sequence similarity, SPANX-A, -B, -C, -D and -E localize to both cytoplasm and nucleus where they are associated with nuclear craters. SPANX-B (Sperm protein associated with the nucleus on the X chromosome B/F) is a 103 amino acid protein that is detected in round and elongating spermatids.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6378R-CY5

Anti-EID3 Rabbit Polyclonal Antibody (Cy5®)

Katalogové číslo: (BOSSBS-6378R-CY5)
Dodavatel: Bioss
Popis: Act as a repressor of nuclear receptor-dependent transcription possibly by interfering with CREBBP-dependent coactivation. May function as a coinhibitor of other CREBBP/EP300-dependent transcription factors.Tissue specificity: Highly expressed in testis.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-4221R

Anti-TM7SF2 Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-4221R)
Dodavatel: Bioss
Popis: Involved in the conversion of lanosterol to cholesterol.Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, and testis, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9719R-A680

Anti-PDE4A8 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-9719R-A680)
Dodavatel: Bioss
Popis: The PDE4A8 is a testis germ cell-specific PDE4A variant. There are two PDE4A variants identified in rat testis (PDE4A8 and an un-characterised 76 kDa PDE4A protein). Spermatogenesis is accompanied by expression of a varied repertoire of PDE4 enzymes at different stages of cell differentiation that presumably perform specialised functions. Confocal microscopic examination revealed the presence of PDE4A8 in primary and secondary spermatids but not in mature spermatozoa. PDE4A8 inhibition results in increased apoptosis of the germ cells accompanied with reduction in the number of mature spermatozoa.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9719R-A555

Anti-PDE4A8 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalogové číslo: (BOSSBS-9719R-A555)
Dodavatel: Bioss
Popis: The PDE4A8 is a testis germ cell-specific PDE4A variant. There are two PDE4A variants identified in rat testis (PDE4A8 and an un-characterized 76 kDa PDE4A protein). Spermatogenesis is accompanied by expression of a varied repertoire of PDE4 enzymes at different stages of cell differentiation that presumably perform specialized functions. Confocal microscopic examination revealed the presence of PDE4A8 in primary and secondary spermatids but not in mature spermatozoa. PDE4A8 inhibition results in increased apoptosis of the germ cells accompanied with reduction in the number of mature spermatozoa.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-15401R-A680

Anti-H2BFWT Rabbit Polyclonal Antibody (ALEXA FLUOR® 680)

Katalogové číslo: (BOSSBS-15401R-A680)
Dodavatel: Bioss
Popis: H2BFWT (H2B histone family member W testis-specific) is a 175 amino acid nuclear membrane histone that belongs to the histone H2B family. In contrast to most H2B histones, H2BFWT does not contain the conserved C-terminal residue involved in monoubiquitination, but is structurally indistinguishable from conventional H2B histones. Also varying from other H2B histones, H2BFWT does not participate in the recruitment of chromosome condensation factors or in the assembly of mitotic chromsomes. Expressed in testis, H2BFWT is present in sperm cells and may be essential to telomere function.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-11558R-A555

Anti-GCNF Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Katalogové číslo: (BOSSBS-11558R-A555)
Dodavatel: Bioss
Popis: Germ cell nuclear factor (GCNF) is an orphan member of the nuclear receptor gene superfamily that influences neurogenesis and germ cell development. GCNF can homodimerize and bind DNA. GCNF regulates paracrine interaction between the oocyte and somatic cells by regulating the expression of BMP-15 and GDF-9, to affect female fertility. GCNF is present in spermatocytes and round spermatids of adult male mouse testis; northern blot and ribonuclease protection assays have shown GCNF is predominant in the testis. The gene expresses three alternatively spliced transcript variants.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13204R-A647

Anti-FOXL2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalogové číslo: (BOSSBS-13204R-A647)
Dodavatel: Bioss
Popis: Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis throught transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-6231R

Anti-MAGEF1 Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-6231R)
Dodavatel: Bioss
Popis: MAGEF1 is a member of the MAGE (melanoma antigen gene) superfamily.Most known members of the MAGE superfamily are expressed in tumors, testis and fetal tissues, which has been described as a cancer/testis or "CT" expression pattern. MAGEF1, however, is expressed in all adult and fetal tissues tested, as well as in many tumor types including ovarian, breast, cervical, melanoma and leukemia. The coding region of MAGE-F1 is contained within a single exon and includes a microsatellite repeat. Several MAGE genes are ubiquitously expressed suggesting a role for MAGE encoded proteins in normal cell physiology.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13204R-CY7

Anti-FOXL2 Rabbit Polyclonal Antibody (Cy7®)

Katalogové číslo: (BOSSBS-13204R-CY7)
Dodavatel: Bioss
Popis: Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis throught transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-13204R

Anti-FOXL2 Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-13204R)
Dodavatel: Bioss
Popis: Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis throught transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9116R

Anti-INHBA Rabbit Polyclonal Antibody

Katalogové číslo: (BOSSBS-9116R)
Dodavatel: Bioss
Popis: Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements. BAGE, also known as B melanoma antigen 1 or cancer/testis antigen 2.1, is a 43 amino acid member of the BAGE family. Generally, BAGE proteins are not expressed in normal tissues, except in testis, but are expressed highly in melanomas, bladder carcinomas, head and neck squamous cell carcinomas, and lung and breast cancer carcinomas. BAGE proteins are not expressed in renal, colorectal and prostatic carcinomas, leukemias and lymphomas.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9116R-A680

Anti-BAGE4 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Katalogové číslo: (BOSSBS-9116R-A680)
Dodavatel: Bioss
Popis: Members of the BAGE gene family encode antigens that are recognised by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements. BAGE, also known as B melanoma antigen 1 or cancer/testis antigen 2.1, is a 43 amino acid member of the BAGE family. Generally, BAGE proteins are not expressed in normal tissues, except in testis, but are expressed highly in melanomas, bladder carcinomas, head and neck squamous cell carcinomas, and lung and breast cancer carcinomas. BAGE proteins are not expressed in renal, colorectal and prostatic carcinomas, leukemias and lymphomas.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9116R-A647

Anti-INHBA Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Katalogové číslo: (BOSSBS-9116R-A647)
Dodavatel: Bioss
Popis: Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements. BAGE, also known as B melanoma antigen 1 or cancer/testis antigen 2.1, is a 43 amino acid member of the BAGE family. Generally, BAGE proteins are not expressed in normal tissues, except in testis, but are expressed highly in melanomas, bladder carcinomas, head and neck squamous cell carcinomas, and lung and breast cancer carcinomas. BAGE proteins are not expressed in renal, colorectal and prostatic carcinomas, leukemias and lymphomas.
Měrná jednotka: 1 * 100 µl
Image Unavailable-BOSSBS-9116R-CY5.5

Anti-INHBA Rabbit Polyclonal Antibody (Cy5.5®)

Katalogové číslo: (BOSSBS-9116R-CY5.5)
Dodavatel: Bioss
Popis: Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements. BAGE, also known as B melanoma antigen 1 or cancer/testis antigen 2.1, is a 43 amino acid member of the BAGE family. Generally, BAGE proteins are not expressed in normal tissues, except in testis, but are expressed highly in melanomas, bladder carcinomas, head and neck squamous cell carcinomas, and lung and breast cancer carcinomas. BAGE proteins are not expressed in renal, colorectal and prostatic carcinomas, leukemias and lymphomas.
Měrná jednotka: 1 * 100 µl
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Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
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