Hledali jste: Akt+inhibitor+VIII

Katalogové číslo: (BOSSBS-8191R-CY5.5)

Dodavatel: Bioss

Popis: Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (ROCK200-341-268)

Dodavatel: Rockland Immunochemicals

Popis: This monoclonal antibody is suitable for immunofluorescence microscopy, FLISA and western blotting. Expect a band approximately 56 kDa in size corresponding to phosphorylated AKT Protein by western blotting in the appropriate cell lysate or extract.

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (ROCK200-343-268)

Dodavatel: Rockland Immunochemicals

Popis: This monoclonal antibody is suitable for immunofluorescence microscopy, FLISA and western blotting. Expect a band approximately 56 kDa in size corresponding to phosphorylated AKT Protein by western blotting in the appropriate cell lysate or extract.

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (BSBTPA2061)

Dodavatel: Boster Bio

Popis: Rabbit IgG polyclonal antibody for Coagulation factor VIII(F8) detection. Tested with WB in Human.

Měrná jednotka: 1 * 0,1 mg

Akce

Katalogové číslo: (BOSSBS-6445R-CY5)

Dodavatel: Bioss

Popis: This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-8191R-A750)

Dodavatel: Bioss

Popis: Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-5209R-CY7)

Dodavatel: Bioss

Popis: AKT3 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT3 is the least studied AKT isoform. It plays an important role in brain development and is crucial for the viability of malignant glioma cells. AKT3 isoform may also be the key molecule in up-regulation and down-regulation of MMP13 via IL13. Required for the coordination of mitochondrial biogenesis with growth factor-induced increases in cellular energy demands. Down-regulation by RNA interference reduces the expression of the phosphorylated form of BAD, resulting in the induction of caspase-dependent apoptosis.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-7703R-CY5)

Dodavatel: Bioss

Popis: Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-6445R-CY7)

Dodavatel: Bioss

Popis: This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-6321R)

Dodavatel: Bioss

Popis: Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-7703R-A680)

Dodavatel: Bioss

Popis: Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-4229R-CY7)

Dodavatel: Bioss

Popis: Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptor (By similarity).

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-6321R-A488)

Dodavatel: Bioss

Popis: Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-6321R-A350)

Dodavatel: Bioss

Popis: Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-6321R-CY7)

Dodavatel: Bioss

Popis: Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-6321R-A750)

Dodavatel: Bioss

Popis: Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. <i>in vitro</i> binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.

Měrná jednotka: 1 * 100 µl

Akce