Hledali jste: 8-(4-Chlorophenylthio)adenosine-3\',5\'-cyclic+monophosphate+sodi

Dodavatel: AAT BIOQUEST

Popis: Adenosine 3’, 5’ cyclic monophosphate (cAMP) is an important second messenger in intracellular signal transduction.

Dodavatel: MP Biomedicals

Popis: IBMX has been shown to be a potent, non-specific inhibitor of adenosine 3',5'-cyclic monophosphate phosphodiesterase (cAMP PDE)4, significantly more effective than theophylline. Also inhibits cGMP phosphodiesterases. IBMX inhibits cyclic nucleotide PDE with subsequent inhibition of cyclic nucleotide hydrolysis, resulting in accumulation of cyclic AMP and guanosine 3',5'-cyclic monophosphate.

Katalogové číslo: (ENZOBMLCN2060001)

Dodavatel: ENZO LIFE SCIENCES

Popis: A cell-permeable cGMP antagonist which is resistant to hydrolysis by cyclic nucleotide phosphodiesterases (Ki=0.5 µM). No metabolic side effects. Significantly more lipophilic and membrane permeant as compared to Rp-cGMPS or Rp-8-Br-cGMPS

Měrná jednotka: 1 * 1 mg

Akce

Katalogové číslo: (PRSI55-781)

Dodavatel: ProSci Inc.

Popis: This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.

Měrná jednotka: 1 * 400 µl

New Product Akce

Dodavatel: ENZO LIFE SCIENCES

Popis: Potent selective inhibitor of cGMP-dependent protein kinase 1α, 1β and type II. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases, no metabolic side effects. Significantly more lipophilic and membrane permeant as compared to Rp-cGMPS or Rp-8-Br-cGMPS.

Katalogové číslo: (PRSI6633)

Dodavatel: ProSci Inc.

Popis: EPAC2 Antibody: EPAC2, also known as Rap guanine nuclear exchange factor 4 and cAMPGEF-II, is belongs to a family of cyclic adenosine monophosphate (cAMP) binding proteins with guanine nucleotide exchange factor. Like the related protein EPAC1, EPAC2 signaling plays a role in numerous cellular processes such as integrin-mediated cell adhesion, muscle contraction, learning and memory, cell proliferation, and inflammation. Recent evidence suggests that EPAC2 induces synapse remodeling and depression, with mutations in its gene being found in patients with autism.

Měrná jednotka: 1 * 100 µG

Akce

Katalogové číslo: (PRSI34-037)

Dodavatel: ProSci Inc.

Popis: Cystic fibrosis transmembrane conductance regulator (CFTR) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (MDR1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.

Měrná jednotka: 1 * 100 µG

New Product Akce

Katalogové číslo: (PRSI33-773)

Dodavatel: ProSci Inc.

Popis: Cystic fibrosis transmembrane conductance regulator (CFTR) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (MDR1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.

Měrná jednotka: 1 * 100 µG

New Product Akce

Dodavatel: Apollo Scientific

Popis: Adenosine 5'-monophosphate monohydrate ≥96%

Dodavatel: Apollo Scientific

Popis: Adenosine 5'-monophosphate disodium salt (from yeast)

Dodavatel: Thermo Fisher Scientific

Popis: Adenosine 5'-monophosphate sodium salt hydrate 99%

Bezpečnostní list

Katalogové číslo: (ENZOALX480014G005)

Dodavatel: ENZO LIFE SCIENCES

Popis: Adenosine 5'-monophosphate disodium salt (AMP disodium salt) ≥98% (by HPLC)

Měrná jednotka: 1 * 5 g

Akce

Dodavatel: Thermo Fisher Scientific

Popis: Adenosine-5'-monophosphoric acid (AMP) 99%

Bezpečnostní list

Dodavatel: Thermo Fisher Scientific

Popis: a useful ligand determinant that facilitate the binding of APS reductase inhibitors and activates adenosine receptor agonists.

Bezpečnostní list Certifikáty

Dodavatel: ENZO LIFE SCIENCES

Popis: PKA activator.

Katalogové číslo: (ENZOALX480085M001)

Dodavatel: ENZO LIFE SCIENCES

Popis: Competitive inhibitor of cyclic AMP-dependent protein kinase I and II.Metabolic stability towards mammalian cyclic nucleotide- responsive phosphodiesterases.
Discriminates between protein kinase A (antagonist) and some other cyclic AMP receptors, e.g. channels or CAP 3 (agonist).Membrane-permeant for several systems (for improved permeability more lipophilic analogues e.g. Rp-8-Br-cAMPS are recommended).

Měrná jednotka: 1 * 1 mg

Akce