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Popis: Promotes cell adhesion and matrix assembly.Tissue specificity: Expressed in dermal papilla and dermal fibroblasts (at protein level). Expressed in heart, thymus, placenta, pancreas, colon, epithelium, spleen and osteoblasts.
Katalogové číslo: BOSSBS-7992R-A555
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Promotes cell adhesion and matrix assembly.Tissue specificity: Expressed in dermal papilla and dermal fibroblasts (at protein level). Expressed in heart, thymus, placenta, pancreas, colon, epithelium, spleen and osteoblasts.
Katalogové číslo: BOSSBS-7992R-FITC
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth (By similarity). Overexpression of HYAL1 suppressed the growth rate of colon carcinoma cell tumors in an experimental model.
Katalogové číslo: BOSSBS-1235R-HRP
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: PCLKC (Protocadherin LKC) belongs to the protocadherin gene family, a subgroup of the cadherin superfamily. It is predominantly expressed in liver, kidney and colon tissues, and has a role in contact inhibition at the lateral surface of epithelial cells. It is a candidate tumor suppressor.
Katalogové číslo: BOSSBS-13729R-CY3
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Required for renal tubular integrity.Tissue specificity: Highest expression in thyroid, adrenal gland and skin. Low levels in spleen, colon and uterus. Overexpressed in breast tumors, with highest expression in infiltrating ductal carcinomas and moderate levels in mucinous adenocarcinoma.
Katalogové číslo: BOSSBS-7815R
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.Tissue specificity:Detected in spleen, thymus, testis, ovary, small intestine and colon, with highest levels of expression in testis and ovary.
Katalogové číslo: BOSSBS-7776R
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: This protein is expressed in colon, lung and liver. Defects in PDGFRL are associated with colorectal cancer.
Katalogové číslo: BOSSBS-6081R-A750
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Expressed in stomach, liver, lung, kidney, prostate, testis, thyroid gland, adrenal gland, brain, heart, skeletal muscle, colon, spleen, small intestine, placenta, blood leukocyte and mammary epithelial cells. Overexpressed in most breast cancer cell lines.
Katalogové číslo: BOSSBS-6605R
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: This protein is expressed in colon, lung and liver. Defects in PDGFRL are associated with colorectal cancer.
Katalogové číslo: BOSSBS-6081R-A488
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: This antibody recognizes human blood group A (monofucosyl and difucosyl A antigens with chain types 1, 2, 3, 4, 5, 6) and Forssmann antigen. It is also reactive with the immuno-dominant A trisaccharide. Blood group antigen expression in human colon cancer was studied by means of two monoclonal antibodies of broad anti-A (HE-14) and anti-type 3 and type 4 chain-based A and H (HE-10) specificity. These antigens were proved to re-appear in tumors of the distal colon, the HE-10 antibody reacting more frequently (9 out of 12 samples) than HE-14 (5 out of 12 samples) and frequently with supra-nuclear staining of the cytoplasm probably in those places of the Golgi apparatus where carbohydrate antigens are synthesized. This staining pattern is characteristic of HE-10 in normal colonic mucosa as well. With HE-14, staining was often absent in less differentiated tumors, while HE-10 did react in such tumors. In some cases, these two antibodies gave different staining patterns in parallel sections from the same tissue sample, primarily at the cellular level. Three out of 12 cases showed blood group antigen expression in the mucosa of the distal colon adjacent to the tumor only when HE-10 Ab was used.
Katalogové číslo: BNUB0235-100
Měrná jednotka: 1 * 100 µl
Dodavatel: Biotium


Popis: PCLKC (Protocadherin LKC) belongs to the protocadherin gene family, a subgroup of the cadherin superfamily. It is predominantly expressed in liver, kidney and colon tissues, and has a role in contact inhibition at the lateral surface of epithelial cells. It is a candidate tumor suppressor.
Katalogové číslo: BOSSBS-13729R-A750
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Involved in the conversion of lanosterol to cholesterol.Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, and testis, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes.
Katalogové číslo: BOSSBS-4221R-CY3
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells.
Katalogové číslo: BOSSBS-6051R-A647
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Recognizes a single glycoprotein of 520 kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as GTQTP (GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.
Katalogové číslo: BNUB0032-100
Měrná jednotka: 1 * 100 µl
Dodavatel: Biotium


Popis: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.Tissue specificity:Detected in spleen, thymus, testis, ovary, small intestine and colon, with highest levels of expression in testis and ovary.
Katalogové číslo: BOSSBS-7776R-A350
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.Tissue specificity:Detected in spleen, thymus, testis, ovary, small intestine and colon, with highest levels of expression in testis and ovary.
Katalogové číslo: BOSSBS-7776R-A555
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


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