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Popis: 3-(Trifluoromethyl)cinnamic acid, Sigma-Aldrich®
Katalogové číslo: SIAL178926-10G
Měrná jednotka: 1 * 10 g
Dodavatel: Merck


Popis: (1,2-Cyclohexylenedinitrilo)tetraacetic Acid, Reagent is an alkyl-substituted amino acid that functions as a chelating agent. This ingredient's source is synthetic. It appears as a solid and is partially soluble in cold water. Its reagent grade means this is the highest quality commercially available for this chemical and that the American Chemical Society has not officially set any specifications for this material.
Katalogové číslo: SPCMC1466-12KGBL
Měrná jednotka: 1 * 12 kg
Dodavatel: Spectrum Chemical


Popis: 3,4-Dimethoxycinnamic acid, Sigma-Aldrich®
Katalogové číslo: SIALD133809-25G
Měrná jednotka: 1 * 25 g
Dodavatel: Merck


Popis: Kyselina trans-1,2-Diaminocyklohexan-N,N,N',N'-tetraoctová monohydrát, Sigma-Aldrich®
Katalogové číslo: SIAL319945-100G
Měrná jednotka: 1 * 100 g
Dodavatel: Merck


Popis: Organic Standard, trans-Ferulic acid
Katalogové číslo: 52229-50MG
Měrná jednotka: 1 * 50 mg
Dodavatel: Merck


Popis: Organic Standard, trans-Cinnamic acid
Katalogové číslo: 97013-50MG
Měrná jednotka: 1 * 50 mg
Dodavatel: Merck


Popis: 3,5-Dimethoxycinnamic acid, Sigma-Aldrich®
Katalogové číslo: SIALD134007-10G
Měrná jednotka: 1 * 10 g
Dodavatel: Merck


Popis: 2-Methylcinnamic acid, Sigma-Aldrich®
Katalogové číslo: SIAL433101-5G
Měrná jednotka: 1 * 5 g
Dodavatel: Merck


Popis: 3-Hydroxy-4-methoxycinnamic acid predominantly trans ≥97%, Sigma-Aldrich®
Katalogové číslo: SIAL103012-1G
Měrná jednotka: 1 * 1 g
Dodavatel: Merck


Popis: 4'-Nitrocinnamic acid for synthesis
Katalogové číslo: 8.18563.0025
Měrná jednotka: 1 * 25 g
Dodavatel: Merck

Popis: 4-Methylcinnamic acid, Sigma-Aldrich®
Katalogové číslo: SIALM35800-5G
Měrná jednotka: 1 * 5 g
Dodavatel: Merck


Popis: Caffeic acid, Sigma-Aldrich®
Katalogové číslo: SIALC0625-2G
Měrná jednotka: 1 * 2 g
Dodavatel: Merck


Popis: 2-(Trifluoromethyl)cinnamic acid, Sigma-Aldrich®
Katalogové číslo: SIAL233080-5G
Měrná jednotka: 1 * 5 g
Dodavatel: Merck


Popis: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. Regulates expression of target genes in a ligand-dependent manner by recruiting chromatin complexes containing KMT2E/MLL5. Mediates retinoic acid-induced granulopoiesis. RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis. Has a role in the survival of early spermatocytes at the beginning prophase of meiosis. In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.
Katalogové číslo: BOSSBS-0251R-A488
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. Regulates expression of target genes in a ligand-dependent manner by recruiting chromatin complexes containing KMT2E/MLL5. Mediates retinoic acid-induced granulopoiesis. RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis. Has a role in the survival of early spermatocytes at the beginning prophase of meiosis. In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.
Katalogové číslo: BOSSBS-0251R-A555
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: GMEB-1 is a 573 amino acid protein that contains one SAND domain and is a member of the KDWK family of combinatorial transcription modulators. Localized to both the cytoplasm and the nucleus, GMEB-1 forms a heterodimer with GMEB-2 (Glucocorticoid modulatory element-binding protein 2) and, once associated with GMEB-2, plays a key role in parvovirus DNA replication. In addition, GMEB-1 functions alone as a trans-acting factor that, by binding to glucocorticoid modulatory elements (GMEs) in TAT (tyrosine aminotransferase) promoters, increases intracellular sensitivity to glucocorticoid concentrations. GMEB-1 also interacts with initiator procaspases and, via this interaction, can inhibit caspase-induced apoptosis. Due to alternative splicing events, GMEB-1 is expressed as two isoforms.
Katalogové číslo: BOSSBS-13454R-HRP
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss