Hledali jste: DL-Tropic+acid

Popis: The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.[provided by RefSeq, Jun 2009].

Katalogové číslo: BOSSBS-9026R-FITC

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.[provided by RefSeq, Jun 2009].

Katalogové číslo: BOSSBS-9026R-A555

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.[provided by RefSeq, Jun 2009].

Katalogové číslo: BOSSBS-9026R-A350

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: Purine nucleoside phosphorylase (PNP), also designated inosine phosphorylase, forms a homotrimer. It belongs to the PNP/MTAP phosphorylase family of proteins. Human PNP catalyzes the reversible phosphorolysis of ribonucleosides and 2’-deoxyribonucleosides with specificity for guanine, hypoxanthine, and their analogs. PNP deficiency is a rare autosomal recessive genetic disease associated with a severe defect in T-lymphocyte function and neurologic disorder in children, comprising four percent of combined immunodeficiency cases. Children with PNP deficiency are highly prone to infections, autoimmune disorders, neurological impairment, and cancer.

Katalogové číslo: BOSSBS-11739R

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: Ham's F-10 was designed for use with Chinese Hamster Ovary (CHO) cells, and has been shown to support the growth of human diploid cells, white blood cells, and primary explants from rat, rabbit, or chicken tissues. This classical media can be used for serum-free growth of some cell lines including CHO cells. Serum supplementation may or may not be necessary depending on the type of cell being cultured. Ham's F-10 contains a wide variety of components, including zinc, hypoxanthine, and thymidine and is buffered with sodium bicarbonate.

Katalogové číslo: HYCLSH30025.01

Měrná jednotka: 1 * 500 mL

Dodavatel: HyClone products (Cytiva)

Akce

Popis: Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro).Involvement in disease;Defects in XDH are the cause of xanthinuria type 1 (XU1) . Xanthinuria is characterized by excretion of very large amounts of xanthine in the urine and a tendency to form xanthine stones. Uric acid is strikingly diminished in serum and urine. XU1 is due to isolated xanthine dehydrogenase. XU1 patients can metabolize allopurinol.

Katalogové číslo: BOSSBS-8552R-HRP

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: Equilibrative nucleoside transporters (ENTs) regulate many physiological processes and are widely distributed in mammals, plants, yeasts, insects, nematodes and protozoans. They enable facilitated diffusion of hydrophilic nucleosides, such as adenosine and nucleoside analogs, across cell membranes. ENTs are required for uptake of antiviral and anticancer nucleoside drugs and influence a variety of physiological processes, such as neurotransmission and platelet aggregation, by regulating the amount of adenoside available to cell surface receptors. Equilibrative nucleoside transporter 2 (ENT2), also designated solute carrier family 29 (nucleoside transporters), member 2, belongs to the SLC29A transporter family and is a mammalian ENT isoform. ENT2 mediates the equilibrative transport of hypoxanthine in addition to nucleosides and is purine-selective.

Katalogové číslo: BOSSBS-13078R

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: Equilibrative nucleoside transporters (ENTs) regulate many physiological processes and are widely distributed in mammals, plants, yeasts, insects, nematodes and protozoans. They enable facilitated diffusion of hydrophilic nucleosides, such as adenosine and nucleoside analogs, across cell membranes. ENTs are required for uptake of antiviral and anticancer nucleoside drugs and influence a variety of physiological processes, such as neurotransmission and platelet aggregation, by regulating the amount of adenoside available to cell surface receptors. Equilibrative nucleoside transporter 2 (ENT2), also designated solute carrier family 29 (nucleoside transporters), member 2, belongs to the SLC29A transporter family and is a mammalian ENT isoform. ENT2 mediates the equilibrative transport of hypoxanthine in addition to nucleosides and is purine-selective.

Katalogové číslo: BOSSBS-13078R-HRP

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: PRTFDC1 Antibody: Phosphoribosyl transferase domain containing 1 (PRTFDC1) is highly homologous to the hypoxanthine phosphoribosyltransferase (HPRT1) and may have arisen from a gene duplication event of a common ancestor gene. Recently, it was shown that CpG islands in the PRTFDC1 promoter could be hypermethylated in ovarian cancers and oral squamous-cell carcinomas (OSCC), leading to gene silencing. Restoration of PRTFDC1 expression in OSCC inhibited cell growth in colony-formation assays, while knockdown of PRTFDC1 expression in OSCC that expressed the gene promoted cell growth. These results suggest that PRTFDC1 can act as a tumor-suppressor gene. At least three isoforms of PRTFDC1 are known to exist.

Katalogové číslo: PRSI4775

Měrná jednotka: 1 * 100 µG

Dodavatel: ProSci Inc.

Akce

Popis: NICOTINAMIDE HYPOXANTHINE*DINUCLEOTIDE S 1 * 100 mg

Katalogové číslo: SIALN6506-100MG

Měrná jednotka: 1 * 100 mg

Dodavatel: Merck

Akce

Popis: NICOTINAMIDE HYPOXANTHINE DINUCLEOTIDE*R 1 * 25 mg

Katalogové číslo: SIALN6756-25MG

Měrná jednotka: 1 * 25 mg

Dodavatel: Merck

Akce

Popis: NICOTINAMIDE HYPOXANTHINE*DINUCLEOTIDE S 1 * 500 mg

Katalogové číslo: SIALN6506-500MG

Měrná jednotka: 1 * 500 mg

Dodavatel: Merck

Akce

Popis: NICOTINAMIDE HYPOXANTHINE*DINUCLEOTIDE S 1 * 25 mg

Katalogové číslo: SIALN6506-25MG

Měrná jednotka: 1 * 25 mg

Dodavatel: Merck

Akce

Popis: XANTHINE/HYPOXANTHINE ASSAY KIT 1 * 1 KIT

Katalogové číslo: SIALMAK186-1KT

Měrná jednotka: 1 * 1 KIT

Dodavatel: Merck

Akce

Popis: NICOTINAMIDE HYPOXANTHINE DINUCLEOTIDE*R 1 * 250 mg

Katalogové číslo: SIALN6756-250MG

Měrná jednotka: 1 * 250 mg

Dodavatel: Merck

Akce

Popis: AZASERINE-HYPOXANTHINE (50X) GAMMA-IRRAD 1 * 1 Vial

Katalogové číslo: SIALA9666-1VL

Měrná jednotka: 1 * 1 Vial

Dodavatel: Merck

Akce