Hledali jste: (S)-Propranolol-O-\u03B2-D-glucuronide

Katalogové číslo: (BOSSBS-4224R-A350)

Dodavatel: Bioss

Popis: UGT1A9 is a UDP glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N termini and identical C termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. UGT1A9 is active on phenols.

Měrná jednotka: 1 * 100 µl

Akce

Dodavatel: Merck

Popis: X-GlcA ((5-bromo-4-chloro-3-indolyl-ß-D-glucuronide) cyclohexylammonium salt), Sigma-Aldrich®

Katalogové číslo: (SIALB8174-5TAB)

Dodavatel: Merck

Popis: X-GlcA ((5-bromo-4-chloro-3-indolyl-ß-D-glucuronide) cyclohexylammonium salt), Sigma-Aldrich®

Měrná jednotka: 1 * 5 Tablet

Akce

Katalogové číslo: (BOSSBS-4224R-CY7)

Dodavatel: Bioss

Popis: UGT1A9 is a UDP glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N termini and identical C termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. UGT1A9 is active on phenols.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-4224R-A647)

Dodavatel: Bioss

Popis: UGT1A9 is a UDP glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N termini and identical C termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. UGT1A9 is active on phenols.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (BOSSBS-4224R-FITC)

Dodavatel: Bioss

Popis: UGT1A9 is a UDP glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N termini and identical C termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. UGT1A9 is active on phenols.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (M-250-1ML)

Dodavatel: Merck

Popis: Mycophenolic acid (MPA), the active moiety of the prodrug mycophenolate mofetil, is widely used in immunosuppressive regimens after kidney, liver or heart transplantation. MPA is metabolized predominantly to the inactive 7-O-glucuronide (MPAG). A minor fraction is converted to the pharmacologically active acyl glucuronide (AcMPAG). All compounds ultimately are eliminated via the kidneys.

Měrná jednotka: 1 * 1 mL

New Product Akce

Dodavatel: Biotium

Popis: This antibody recognizes a protein of about 60 kDa, which is identified as human UGT1A9. It does not cross-react with the other UGT1A isoforms including UGT1A7, UGT1A8, and UGT1A10 and shows a high degree of specificity. UGT1A9 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This MAb binds to human hepatocytes and the majority of human hepatocellular carcinomas (HCC s). In frozen sections, it stains hepatic cells and may be used as a marker of the liver. This MAb also binds to cell preparations of hepatocellular carcinoma biopsies or cell lines.

Katalogové číslo: (BTIUBNUM1229-50)

Dodavatel: Biotium

Popis: This antibody recognizes a protein of about 60 kDa, which is identified as human UGT1A9. It does not cross-react with the other UGT1A isoforms including UGT1A7, UGT1A8, and UGT1A10 and shows a high degree of specificity. UGT1A9 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This MAb binds to human hepatocytes and the majority of human hepatocellular carcinomas (HCC s). In frozen sections, it stains hepatic cells and may be used as a marker of the liver. This MAb also binds to cell preparations of hepatocellular carcinoma biopsies or cell lines.

Měrná jednotka: 1 * 50 µl

Akce

Katalogové číslo: (BOSSBS-4224R-A488)

Dodavatel: Bioss

Popis: UGT1A9 is a UDP glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N termini and identical C termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. UGT1A9 is active on phenols.

Měrná jednotka: 1 * 100 µl

Akce

Katalogové číslo: (N-104-1ML)

Dodavatel: Merck

Popis: Organic Standard, 6beta-Naltrexol-3-beta-D-glucuronide

Měrná jednotka: 1 * 1 mL

Akce

Dodavatel: Merck

Popis: Ethyl ß-D-glucuronide is a primary urinary metabolite of alcohol and can be used as a biomarker for the monitoring of alcohol consumption.

Katalogové číslo: (E-015-1ML)

Dodavatel: Merck

Popis: Ethyl ß-D-glucuronide is a primary urinary metabolite of alcohol and can be used as a biomarker for the monitoring of alchohol consumption.

Měrná jednotka: 1 * 1 mL

Akce

Katalogové číslo: (T-060-1ML)

Dodavatel: Merck

Popis: Organic Standard, Tapentadol-beta-D-glucuronide solution, ampoule of 1 ml

Měrná jednotka: 1 * 1 mL

Akce

Katalogové číslo: (P-082-1ML)

Dodavatel: Merck

Popis: Organic Standard, Propofol beta-D-glucuronide sodium salt, ampoule of 1 ml

Měrná jednotka: 1 * 1 mL

Akce

Katalogové číslo: (E-063-1ML)

Dodavatel: Merck

Popis: Ethyl ß-D-glucuronide is a primary urinary metabolite of alcohol and can be used as a biomarker for the monitoring of alchohol consumption.

Měrná jednotka: 1 * 1 mL

Akce