Nonactin (from Streptomyces griseus) ≥98% (by TLC)
Dodavatel: ENZO LIFE SCIENCES
Synonyms:
Polynactin, Werramycin A
Macrotetrolide antibiotic. Monovalent cation ionophore with high selectivity for ammonium and potassium. Specifically inhibits the processing of cytoplasmic precursor proteins destined for the mitochondria. Inhibits the effects on P170 glycoprotein-mediated efflux of chemotherapeutic agents in multidrug resistant (MDR) cancer cells.
- Monovalent cation ionophore
White to off-white crystalline solid.
Soluble in DMSO (10mg/ml), dichloromethane (10mg/ml), methanol, 100% ethanol; insoluble in water.
Vzorec:
C₄₀H₆₄O₁₂ MW: 736,9 g/mol Storage Temperature: Freezer |
CAS číslo:
6833-84-7 |
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