Tacrolimus ≥98%, crystalline powder
Dodavatel: ENZO LIFE SCIENCES
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Nebezpečí
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Immunosuppressant.
Immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK506 binding protein and to inhibit the Ca²⁺-dependent phosphatase and protein phosphatase 2B (PP2B; calcineurin). Activates NF-κB through phosphorylation and degradation of IκBα.
Soluble in DMSO, 100% ethanol, methanol, ethyl acetate or acetone; insoluble in water.
Vzorec:
C₄₄H₆₉NO₁₂ Storage Temperature: Freezer |
MDL Number:
MFCD00869853 CAS číslo: 104987-11-3 UN: 2811 ADR: 6.1,III Merck Index: 14,09025 |
Výsledky specifikačního testu
Purity | ≥98% (Assay) |
Source | Isolated from Streptomyces tsukubaensi |
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