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trans-Ned-19

Dodavatel: ENZO LIFE SCIENCES

ALX270503M001 ALX270503MC05
ENZOALX270503M001EA 12120 CZK
ENZOALX270503M001 ENZOALX270503MC05
trans-Ned-19
trans-Ned-19

Cell permeable, selective and potent inhibitor of nicotinic acid adenine dinucleotide phosphate (NAADP) receptor in mammalian cells and sea urchin eggs. Blocks NAADP signaling. Inhibits Ca2+ release: trans-Ned-19 (IC50 = 6nM); cis-Ned-19 (IC50 = 800nM). [32P] NAADP binding: trans-Ned-19 (IC50 = 0.4nM); cis-Ned-19 (IC50 = 15µM).
Inhibits Ca2+ release from lysosomes. Noncompetitive antagonist. Fluorescent.


Synthetic

Vzorec: C₃₀H₃₁FN₄O₃
MW: 514,601 g/mol
MDL Number: MFCD02057367
CAS číslo: 1354235-96-3

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