Dynasore ≥98% (by NMR)
Dodavatel: ENZO LIFE SCIENCES
Synonyms:
N'-(3,4-Dihydroxybenzylidene)-3-hydroxy-2-naphthohydrazide, 3-Hydroxynaphthalene-2-carboxylic acid (3,4-Dihydroxybenzylidene)hydrazide
GTPase inhibitor
Small molecule GTPase inhibitor targeting Dynamin-1, Dynamin-2 and Drp1 (mitochondrial Dynamin). Noncompetitive inhibitor of Dynamin GTPase activity. Blocks Dynamin-dependent endocytosis in cells (including neurons). Fast acting (seconds). Strong, dose dependent block of the traffic and accumulation of transferrin with 80µM dynasore (IC50 = 15µM). Has also been shown to block human papillomavirus type 16 (HPV16) and bovine papillomavirus type 1 (BPV1) (pseudovirions) infections.
Vzorec:
C₁₈H₁₄N₂O₄ MW: 322.32 g/mol |
MDL Number:
MFCD00292551 CAS číslo: 304448-55-3 |
Learn more

About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...