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Dynasore ≥98% (by NMR)

Dodavatel: ENZO LIFE SCIENCES

Synonyms: N'-(3,4-Dihydroxybenzylidene)-3-hydroxy-2-naphthohydrazide, 3-Hydroxynaphthalene-2-carboxylic acid (3,4-Dihydroxybenzylidene)hydrazide

ALX270502M005 ALX270502M025
ENZOALX270502M005EA 2110 CZK
ENZOALX270502M005 ENZOALX270502M025
Dynasore ≥98% (by NMR)
Dynasore

GTPase inhibitor


Small molecule GTPase inhibitor targeting Dynamin-1, Dynamin-2 and Drp1 (mitochondrial Dynamin). Noncompetitive inhibitor of Dynamin GTPase activity. Blocks Dynamin-dependent endocytosis in cells (including neurons). Fast acting (seconds). Strong, dose dependent block of the traffic and accumulation of transferrin with 80µM dynasore (IC50 = 15µM). Has also been shown to block human papillomavirus type 16 (HPV16) and bovine papillomavirus type 1 (BPV1) (pseudovirions) infections.

Vzorec: C₁₈H₁₄N₂O₄
MW: 322.32 g/mol
MDL Number: MFCD00292551
CAS číslo: 304448-55-3

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