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RepSox ≥97% (by HPLC)

Dodavatel: ENZO LIFE SCIENCES

Synonyms: 2-[3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine, 2-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine, ALK 5 Inhibitor II, TGF-beta RI Kinase Inhibitor II

ALX270445M001 ALX270445M005
ENZOALX270445M001EA 3400 CZK
ENZOALX270445M001 ENZOALX270445M005
RepSox ≥97% (by HPLC)
RepSox

Cell permeable, potent, selective and ATP-competitive inhibitor of TGF-β RI kinase (IC50=23nM, 4nM and 18nM for binding, auto-phosphorylation and cellular assay in HepG2 cells of TGF-β RI kinase, respectively). Minimally affects a panel of 9 closely related kinases including p38 MAPK (IC50>16µM).


White to off-white or yellow solid.


5mg/ml soluble in DMSO or methanol.

Vzorec: C₁₇H₁₃N₅
MW: 287,326 g/mol
Storage Temperature: Freezer
MDL Number: MFCD09037561
CAS číslo: 446859-33-2

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