RepSox ≥97% (by HPLC)
Dodavatel: ENZO LIFE SCIENCES
Synonyms:
2-[3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine, 2-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine, ALK 5 Inhibitor II, TGF-beta RI Kinase Inhibitor II
Cell permeable, potent, selective and ATP-competitive inhibitor of TGF-β RI kinase (IC50=23nM, 4nM and 18nM for binding, auto-phosphorylation and cellular assay in HepG2 cells of TGF-β RI kinase, respectively). Minimally affects a panel of 9 closely related kinases including p38 MAPK (IC50>16µM).
White to off-white or yellow solid.
5mg/ml soluble in DMSO or methanol.
Vzorec:
C₁₇H₁₃N₅ MW: 287,326 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD09037561 CAS číslo: 446859-33-2 |
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