XAV939 ≥98% (by TLC)
Dodavatel: ENZO LIFE SCIENCES
BMLWN1000005
BMLWN1000025
ENZOBMLWN1000005EA
1920
CZK
ENZOBMLWN1000005
ENZOBMLWN1000025
XAV939 ≥98% (by TLC)
XAV939
PARP5a inhibitor
Potent inhibitor of Tankyrase 1 (IC50=11nM) and Tankyrase 2 (IC50=4nM). Inhibition of tankyrase promotes stabilization of axin resulting in β-catenin degradation and Wnt signalling disruption. Inhibits proliferation of the μ-catenin-dependent colon carcinoma cell line DLD-1. Promotes cardiomyogenic development in mesoderm progenitor cells.
Vzorec:
C₁₄H₁₁F₃N₂OS |
MDL Number:
MFCD16879017 CAS číslo: 284028-89-3 |
|
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