H-89 dihydrochloride ≥99% (by TLC)
Dodavatel: ENZO LIFE SCIENCES
BMLEI1960005
BMLEI1960025
ENZOBMLEI1960005EA
4710
CZK
ENZOBMLEI1960005
ENZOBMLEI1960025
H-89 dihydrochloride ≥99% (by TLC)
H-89 dihydrochloride
Protein kinase inhibitor
Cell permeable potent and selective inhibitor of cAMP- and cGMP-dependent protein kinases (PKA, Ki=48nM, and PKG) and protein kinase Cµ (PKCµ). In contrast, most other protein kinase C (PKC) isotypes are much more weakly inhibited. Also inhibits Ca2+/calmodulin-dependent protein kinase II, casein kinase I and myosin light chain kinase. Induces apoptosis. Concentration range for cultured cells 30-100μM: osteoblastic cells, renal proximal tubule cells and Xenopus oocytes.
Vzorec:
C₂₀H₂₀BrN₃O₂S·2HCl MW: 519.28 g/mol |
CAS číslo:
127243-85-0 |
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