Lorcainide hydrochloride ≥98% (by TLC)
Dodavatel: ENZO LIFE SCIENCES
Na+ channel blocker
Possesses both local anesthetic and antiarrhythmic properties (class 1C agent). Elevates the ventricular fibrillation threshold and protects against ouabain-induced arrhythmias in animal models. Its mechamism of action is primarly inhibition of sodium channels in a voltage- and frequency-dependent fashion. Also inhibits the microsomal Na+,K+-ATPase in a concentration-dependent manner (IC50=33.5µM) . Reduces neuronal death in cellular models of hypoxic injury when combined with a glutamate receptor antagonist and blocks aconitine-induced mortality in a rat model (ED50=30mg/kg).
Vzorec:
C₂₂H₂₈Cl₂N₂O MW: 407.379 g/mol |
MDL Number:
MFCD00055196 CAS číslo: 58934-46-6 |
|
Learn more

About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...