Paxilline ≥97% (by HPLC)
Dodavatel: ENZO LIFE SCIENCES
BMLKC1550005
BMLKC1550025
ENZOBMLKC1550005EA
4710
CZK
ENZOBMLKC1550005
ENZOBMLKC1550025
Paxilline ≥97% (by HPLC)
Paxilline
K+ channel blocker
Paxilline is an indole alkaloid isolated from Penicillium paxilli. It is a selective and reversible blocker of the smooth muscle high conductance Ca2+-activated K+ (maxi-K) channel (70% block at 10 nM). In neutrophils, Paxilline blockage of BKCa channels decreased the alkalinization of phagocytic vacuoles and inhibited the microbicidal process. Inhibitor of the cerebellar inositol 1,4,5-triphosphate (InsP(3)) receptor.
Vzorec:
C₂₇H₃₃NO₄ |
MDL Number:
MFCD00083464 CAS číslo: 57186-25-1 |
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