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Human recombinant FGF21 (from E. coli)

Dodavatel: Shenandoah Biotechnology

100-148AF100UG 100-148AF-1MG 100-148AF-20UG 100-148AF500UG 100-148AF-5UG
SHBT100-148AF100UGEA 14280 CZK
SHBT100-148AF100UG SHBT100-148AF-1MG SHBT100-148AF-20UG SHBT100-148AF500UG SHBT100-148AF-5UG
Human recombinant FGF21 (from E. coli)
Proteiny

Fibroblast growth factor 21 (FGF-21) is an endocrine hormone that regulates energy homeostasis and exerts cardioprotective functions during heart injury. FGF-21 is expressed in the liver, pancreas, heart, and adipose tissues. FGF-21 signaling is activated through the FGFR1c receptor and β-Klotho co-receptor. FGF-21 is an important regulator of glucose uptake and reduces cell apoptosis under stress conditions.


  • Animal-free
  • Produced from genetically modified E. coli
  • Monomeric protein containing 182 amino acids


Informace o dodávce: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.


Upozornení: This product is for research use only and is not for use in humans.

Objednat

Produktová specifikace

Název proteinu/peptidu FGF-21 FGF21
Environmentally Preferable
Proteinová synonyma FGFL Fibroblast Growth Factor-21|FGF-21|FGFL
Typ proteinu/peptidu Recombinant Recombinant
Proteinový podtyp Cytokine Cytokine
Druhy Human Human
Zdroj E. coli E. coli
Spojení Unconjugated Unconjugated
Identifikační číslo genu Q9NSA1 Q9NSA1
Sekvence MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS
Počet aminokyselin 182
Bez obsahu proteázy N N
Bez obsahu živočichů Y Y
Bez nukleáz N N
Bez nosiče Y Y
Bez obsahu endotoxinů N N
Úroveň endotoxinů Low Low
Obsah endotoxinů Endotoxin LAL (EU/µg) ≤0,1 Endotoxin LAL (EU/µg) ≤0,1
Biologická aktivita Bioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mg Bioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mg
Čistota ≥95% ≥95%
Třída RUO RUO
Formulace 10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5 10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5
Molekulární hmotnost 19,5 kDa 19,5 kDa
Pokyny pro rekonstituce Sterile water at 0.1 mg/ml Sterile water at 0.1 mg/ml
Podmínky uskladnění –20 °C –20 °C
Transportní teplota RT RT
Testované aplikace Bioassay Bioassay

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