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Human recombinant Amphiregulin (from E. coli)

Dodavatel: Shenandoah Biotechnology

100-206-10UG 100-206-50UG 100-206-100UG 100-206-500UG 100-206-1MG
SHBT100-206-10UGEA 2070 CZK
SHBT100-206-10UG SHBT100-206-50UG SHBT100-206-100UG SHBT100-206-500UG SHBT100-206-1MG
Human recombinant Amphiregulin (from E. coli)
Proteiny

Amphiregulin (AR) is a member of the epidermal growth factor (EGF) family.


  • Produced from genetically modified E. coli
  • Monomeric protein, containing 87 amino acids
  • Promotes ductal outgrowth and mammary branching
  • Up-regulated at puberty
  • Functions as a mitogen and prevents hepatocyte apoptosis in liver


AR is an autocrine growth factor and functions to regulate cell proliferation and survival through binding the EGF receptor (EGFR). In a cancer, AR protects against human adenocarcinoma apoptosis, promotes tumor cell growth, and functions as an oncogenic factor in the hippo pathway. AR levels are increased in the brain following stress events, such as inflammation, ischemia, and hypoxia. It also promotes the proliferation of neural stem cells and epithelial cells, including keratinocytes and mammary epithelium.


Informace o dodávce: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.


Upozornení: This product is for research use only and is not for use in humans.

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