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Anti-CD86 Mouse Monoclonal Antibody (CF647) [clone: C86/1146]

Dodavatel: Biotium
BNC471146-500 BNC471146-100
BNC471146-500EA 15090 CZK
BNC471146-500 BNC471146-100
Anti-CD86 Mouse Monoclonal Antibody (CF647) [clone: C86/1146]
Protilátky
Recognizes a protein of 70 kDa, which is identified as CD86. CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.

Type: Primary
Antigen: CD86
Clonality: Monoclonal
Clone: C86/1146
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human, Mouse, Rat
Objednat

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