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Anti-CDKN1A Mouse Monoclonal Antibody [clone: CIP1/823 DCS-60.2]

Dodavatel: Biotium
BNUB1135-500 BNUB1135-100
BNUB1135-500EA 14540 CZK
BNUB1135-500 BNUB1135-100
Anti-CDKN1A Mouse Monoclonal Antibody [clone: CIP1/823 DCS-60.2]
Protilátky
This MAb recognizes a 21 kDa protein, identified as the p21WAF1 tumor suppressor protein. This MAb is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdk's and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).

  • Purified

Type: Primary
Antigen: CDKN1A
Clonality: Monoclonal
Clone: CIP1/823 DCS-60.2
Conjugation: Purified
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Human
Objednat

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