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Anti-MITF Mouse Monoclonal Antibody (CF488A) [clone: D5 MITF/915]

Dodavatel: Biotium
BNC880950-500 BNC880950-100
BNC880950-500EA 15940 CZK
BNC880950-500 BNC880950-100
Anti-MITF Mouse Monoclonal Antibody (CF488A) [clone: D5 MITF/915]
Protilátky
MITF (microphthalmia transcription factor) is a basic helix-loop-helix-leucine-zipper (bHLH-Zip) transcription factor that regulates the development and survival of melanocytes and retinal pigment epithelium, and also is involved in transcription of pigmentation enzyme genes such as tyrosinase TRP1 and TRP2. MITF has been shown to be phosphorylated by MAP kinase in response to c-kit activation, resulting in upregulation of MITF transcriptional activity. Mutations of the MITF gene are associated with the autosomal dominant hereditary deafness and pigmentation condition, Waardenburg SyndromeMore Product Information
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