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Anti-TYR Mouse Monoclonal Antibody (CF405S) [clone: OCA1/812]

Dodavatel: Biotium
BNC040812-500 BNC040812-100
BNC040812-500EA 15940 CZK
BNC040812-500 BNC040812-100
Anti-TYR Mouse Monoclonal Antibody (CF405S) [clone: OCA1/812]
Protilátky
Recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cellMore Product Information
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Produktová specifikace

Symbol antigenu TYR
Název antigenu Tyrosinase
Environmentally Preferable
Synonyma antigenu Tumor rejection antigen AB|ATN|CMM8|SHEP3|Oculocutaneous albinism IA|Monophenol monooxygenase|OCA1A|OCA1|TYR|LB24-AB|SK29-AB
Druh protilátky Primární
Klonovalita Monoclonal
Spojení CF® 405S
Klon Clone OCA1/812
Reaktivita Human
Hostitel Mouse
Identifikační číslo genu 503555
Izotyp IgG2a kappa
ELISA Yes
Imunochemie Yes
ImunoFluorescence Yes
Koncentrace 0,1 mg/ml
Skladovací pufr PBS/0,1% BSA/0,05% azide

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