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Anti-TYMS Mouse Monoclonal Antibody (CF647) [clone: TS106 TMS715]

Dodavatel: Biotium
BNC470716-500 BNC470716-100
BNC470716-500EA 15940 CZK
BNC470716-500 BNC470716-100
Anti-TYMS Mouse Monoclonal Antibody (CF647) [clone: TS106 TMS715]
Protilátky
This antibody recognizes a protein of 36 kDa, identified as Thymidylate Synthase (TS) (EC 2.1.1.45). TS converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. ExpressionMore Product Information
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Produktová specifikace

Symbol antigenu TYMS
Environmentally Preferable
Název antigenu Thymidylate Synthase
Synonyma antigenu TSase|TS|TMS|Tyms thymidylate synthetase|dTMP synthase|TYMS protein
Druh protilátky Primární
Klonovalita Monoclonal
Spojení CF® 647
Klon Clone TS106 TMS715
Reaktivita Human
Hostitel Mouse
Identifikační číslo genu 369762
Izotyp IgGs
Imunochemie Yes
ImunoFluorescence Yes
Koncentrace 0,1 mg/ml
Skladovací pufr PBS/0,1% BSA/0,05% azide

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