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Anti-TOP1MT Mouse Monoclonal Antibody (Biotin) [clone: TOP1MT/488]

Dodavatel: Biotium
BNCB0488-500 BNCB0488-100
BNCB0488-500EA 15090 CZK
BNCB0488-500 BNCB0488-100
Anti-TOP1MT Mouse Monoclonal Antibody (Biotin) [clone: TOP1MT/488]
Protilátky
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.

Type: Primary
Antigen: TOP1MT
Clonality: Monoclonal
Clone: TOP1MT/488
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG2b kappa
Reactivity: Human
Objednat

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