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Anti-NEFH Mouse Monoclonal Antibody (CF488A) [clone: RT-97]

Dodavatel: Biotium
BNC880454-500 BNC880454-100
BNC880454-500EA 15090 CZK
BNC880454-500 BNC880454-100
Anti-NEFH Mouse Monoclonal Antibody (CF488A) [clone: RT-97]
Protilátky
This MAb reacts with a 200 kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.

Type: Primary
Antigen: NEFH
Clonality: Monoclonal
Clone: RT-97
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Chicken, Human, Mouse, Pig, Rat
Objednat

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