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Anti-CD47 Mouse Monoclonal Antibody (CF647) [clone: B6H12.2]

Dodavatel: Biotium
BNC470437-500 BNC470437-100
BNC470437-500EA 15940 CZK
BNC470437-500 BNC470437-100
Anti-CD47 Mouse Monoclonal Antibody (CF647) [clone: B6H12.2]
Protilátky
This antibody reacts with Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

Type: Primary
Antigen: CD47
Clonality: Monoclonal
Clone: B6H12.2
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human, Mouse
Objednat

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