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Anti-CD33 Mouse Monoclonal Antibody (CF594) [clone: WM53]

Dodavatel: Biotium
BNC940166-500 BNC940166-100
BNC940166-500EA 15940 CZK
BNC940166-500 BNC940166-100
Anti-CD33 Mouse Monoclonal Antibody (CF594) [clone: WM53]
Protilátky
Recognizes a 67 kDa glycoprotein, which is identified as CD33 (HLDA IV; WS Code M-505). CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immuno-receptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is aMore Product Information
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