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Anti-TYR Mouse Monoclonal Antibody (CF647) [clone: T311]

Dodavatel: Biotium
BNC470012-500 BNC470012-100
BNC470012-500EA 15940 CZK
BNC470012-500 BNC470012-100
Anti-TYR Mouse Monoclonal Antibody (CF647) [clone: T311]
Protilátky
Recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cellMore Product Information
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