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Anti-CD8A Rat Monoclonal Antibody (violetFluor® 450) [clone: 2.43]

Dodavatel: Tonbo Biosciences
75-1886-U025 75-1886-U100
75-1886-U025EA 1990 CZK
75-1886-U025 75-1886-U100
Anti-CD8A Rat Monoclonal Antibody (violetFluor® 450) [clone: 2.43]
Protilátky
The 2.43 antibody reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation induced by binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck and facilitate intracellular signaling events that lead to T cell activation, development, and cytotoxicMore Product Information
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