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Anti-CD4 Mouse Monoclonal Antibody (Peridinin Chlorophyll/Cy5.5®) [clone: RPA-T4]

Dodavatel: Tonbo Biosciences
65-0049-T100 65-0049-T025
65-0049-T100EA 3580 CZK
65-0049-T100 65-0049-T025
Anti-CD4 Mouse Monoclonal Antibody (Peridinin Chlorophyll/Cy5.5®) [clone: RPA-T4]
Protilátky
The RPA-T4 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17More Product Information
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Produktová specifikace

Symbol antigenu CD4
Název antigenu CD4 molecule
Environmentally Preferable
Synonyma antigenu L3T4|p55|CD4mut|Ly-4|W3/25
Druh protilátky Primární
Klonovalita Monoclonal
Spojení PerCP (Peridinin-Chlorophyll Protein Complex)/Cy5.5®
Klon RPA-T4
Reaktivita Chimpanzee,Human
Hostitel Mouse
Identifikační číslo genu 920
Izotyp IgG1 kappa
Imunochemie Yes
Imunoprecipitace Yes
Průtoková cytometrie Yes
Křížová adsorbce none
Skladovací teplota Cool
Transportní teplota Ice

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