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Anti-TNFRSF18 Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: DTA-1]

Dodavatel: Tonbo Biosciences
50-5874-U100 50-5874-U025
50-5874-U100EA 5350 CZK
50-5874-U100 50-5874-U025
Anti-TNFRSF18 Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: DTA-1]
Protilátky
The DTA-1 antibody reacts with mouse CD357, also known as GITR or AITR (in humans), a 66-70 kDa member of the Tumor Necrosis Factor superfamily (TNFRSF18). GITR is primarily found on T cells, and its function may vary depending on the T cell type where it is expressed. GITR is upregulated on activated T cells where it provides co-stimulation, yet GITR may promote the inhibition of CD4+ CD25+ Treg cells, where it is expressed at high levels. GITR ligand (GITRL) is found on B cells, macrophages, dendritic and endothelial cells, and is implicated in regulating both innate and adaptive immuneMore Product Information
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