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Popis: UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
Katalogové číslo: BNCB1222-100
Měrná jednotka: 1 * 100 µl
Dodavatel: Biotium


Popis: UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
Katalogové číslo: BNC040956-100
Měrná jednotka: 1 * 100 µl
Dodavatel: Biotium


Popis: UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
Katalogové číslo: BNC941222-100
Měrná jednotka: 1 * 100 µl
Dodavatel: Biotium


Popis: UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
Katalogové číslo: BNC471222-100
Měrná jednotka: 1 * 100 µl
Dodavatel: Biotium


Popis: Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide. Isoform 2: has weaker endopeptidase activity compared to isoform 1.
Katalogové číslo: BOSSBS-7685R-CY7
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Pro inflammatory cytokines activate the transcription factor NF kappa B by stimulating the activity of a protein kinase that phosphorylates Ikappa B, an inhibitor of NF kappa B, at sites that trigger its ubiquitination and degradation. A large, cytokine responsive Ikappa B kinase (IKK) complex has been purified and the genes encoding 2 of its subunits have been cloned. These subunits, IKK alpha and Ikk beta, are protein kinases whose function is needed for NF kappa B activation by pro inflammatory stimuli. IKK is composed of similar amounts of IKK alpha, Ikk beta, which are differentially processed forms of a third subunit, IKK gamma. IKK gamma interacts preferentially with IKK beta and is required for the activation of the IKK complex.
Katalogové číslo: BOSSBS-3228R-HRP
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Pro inflammatory cytokines activate the transcription factor NF kappa B by stimulating the activity of a protein kinase that phosphorylates Ikappa B, an inhibitor of NF kappa B, at sites that trigger its ubiquitination and degradation. A large, cytokine responsive Ikappa B kinase (IKK) complex has been purified and the genes encoding 2 of its subunits have been cloned. These subunits, IKK alpha and Ikk beta, are protein kinases whose function is needed for NF kappa B activation by pro inflammatory stimuli. IKK is composed of similar amounts of IKK alpha, Ikk beta, which are differentially processed forms of a third subunit, IKK gamma. IKK gamma interacts preferentially with IKK beta and is required for the activation of the IKK complex.
Katalogové číslo: BOSSBS-3228R-FITC
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: ESD safety ankle boot made from hydrophobised microfibre/hydrophobised textile Cordura® upper and a PU/PU sole (Ergo-Active 2). Type 2: For average wide feet with long toes, medium ball and heel width, flat ball angle.
Katalogové číslo: ELTN7685502/46
Měrná jednotka: 1 * 1 PÁR
Dodavatel: ELTEN

Environmentally Preferable New Product


Popis: The fidelity of protein synthesis requires efficient discrimination of amino acid substrates by aminoacyl-tRNA synthetases. Aminoacyl-tRNA synthetases function to catalyze the aminoacylation of tRNAs by their corresponding amino acids, thus linking amino acids with tRNA-contained nucleotide triplets. ProRS (Prolyl-tRNA synthetase), also known as EPRS, EARS, PARS, QARS, QPRS, PIG32 or GLUPRORS, is a 1,512 amino acid protein that contains three WHEP-TRS domains and belongs to both the class-I and class-II aminoacyl-tRNA synthetase family. Functioning as a component of the multisynthase complex, ProRS uses ATP to catalyze the conversion of L-glutamate and tRNA(Glu) to L-glutamyl-tRNA(Glu), as well as the conversion of L-proline and tRNA(Pro) to L-prolyl-tRNA(Pro).
Katalogové číslo: BOSSBS-13393R-A350
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: 100% metal- and leather-free, lightweight ESD safety ankle boots made from hydrophobised microfibre and hydrophobised CORDURA® (tear and abrasion resistant, dirt and water repellent), a padded tongue plus a slip resistant, dual-density TPU/PU sole (Trainers).
Katalogové číslo: 114-6259
Měrná jednotka: 1 * 1 PÁR
Dodavatel: ELTEN

Environmentally Preferable


Popis: Light module warm white 2,700 K: light strips arranged on the side walls of the interior, 10 strips for model 110, 14 for model 260/410/750, pro­gramme-controlled dimming from 0 to 100 % (in 1 % steps), ramp programming in combination with temperature and humidity; not in combination with F6, F7, D8, HPP410eco
Katalogové číslo: MEMMHPP750ECOT9
Měrná jednotka: 1 * 1 KS
Dodavatel: MEMMERT


Popis: Pro inflammatory cytokines activate the transcription factor NF kappa B by stimulating the activity of a protein kinase that phosphorylates Ikappa B, an inhibitor of NF kappa B, at sites that trigger its ubiquitination and degradation. A large, cytokine responsive Ikappa B kinase (IKK) complex has been purified and the genes encoding 2 of its subunits have been cloned. These subunits, IKK alpha and Ikk beta, are protein kinases whose function is needed for NF kappa B activation by pro inflammatory stimuli. IKK is composed of similar amounts of IKK alpha, Ikk beta, which are differentially processed forms of a third subunit, IKK gamma. IKK gamma interacts preferentially with IKK beta and is required for the activation of the IKK complex.
Katalogové číslo: BOSSBS-3228R-A680
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss


Popis: Thanks to its excellent discharge capability, the shoe is suitable for work in ESD sensitive or electrostatically protected areas (EPA).
Katalogové číslo: ELTN768121/44
Měrná jednotka: 1 * 1 PÁR
Dodavatel: ELTEN

Environmentally Preferable


Popis: Gilson’s reusable, silica-free centrifugal partition chromatography (CPC) columns offer high injection capacities of milligram to multi-kilograms resulting in 95% recoveries with 99% purity or better.
Katalogové číslo: GILI21141010
Měrná jednotka: 1 * 1 KS
Dodavatel: GILSON LCMS


Popis: Anti-POMC Goat Polyclonal Antibody
Katalogové číslo: USBIP9025-04F
Měrná jednotka: 1 * 100 µG
Dodavatel: US Biological


Popis: The MAP4 (Microtubule associated protein 4)is a non neuronal microtubule associated protein. It promotes microtubule assembly.The phosphorylation of the Pro rich region in the C-terminus negatively regulates MAP4 activity to promote microtubule assembly.
Katalogové číslo: BOSSBS-5439R
Měrná jednotka: 1 * 100 µl
Dodavatel: Bioss