Hledali jste: 6-Acetyl-1H-indazole

Popis: A cell permeable, highly specific, potent and ATP-competitive inhibitor of Rho kinase (ROCK) (Ki=1.6nM). Exhibits a much weaker affinity for other serine/threonine kinases (Ki=630nM for PKA, 9.27mM for PKC and 10.1mM for MLCK). More potent and selective than Y-27632. Inhibits the phosphorylation of MARCKS in cells stimulated by lysophosphatidic acid. Inhibits EP3-stimulated NO formation. Prevents fragmentation of apoptotic cells. Relieves neuropathic pain.

Katalogové číslo: ENZOALX270423M025

Měrná jednotka: 1 * 25 mg

Dodavatel: ENZO LIFE SCIENCES

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