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Image Unavailable-40-7102-U100

Anti-IL-10 Rat Monoclonal Antibody (In Vivo Ready™) [clone: JES5-2A5]

Katalogové číslo: (40-7102-U100)
Dodavatel: Tonbo Biosciences
Popis: The JES5-2A5 antibody is specific for mouse IL-10. IL-10 has numerous biological activities including the ability to inhibit both the synthesis of Th1 cytokines and proliferation of T cells. In the mouse, IL-10 is produced by phagocytic cells, conventional dendritic, cells, T cells, B cells, and NK cells. The JES5-2A5 antibody is a neutralizing antibody.
Měrná jednotka: 1 * 100 µG
Image Unavailable-80-4724-U100

Mouse IgG2a Isotype Control [clone: C1.18.4] (redFluor® 710)

Katalogové číslo: (80-4724-U100)
Dodavatel: Tonbo Biosciences
Popis: The C1.18.4 immunoglobulin is useful as an isotype-matched control. The C.1.18.4 immunolglobulin has an unknown binding specificity and is used as an isotype control for mouse IgG2a antibodies.
Měrná jednotka: 1 * 100 µG
Product Image-70-4321-U100

Rat IgG2a kappa Isotype Control [clone: 2A3]

Katalogové číslo: (70-4321-U100)
Dodavatel: Tonbo Biosciences
Popis: Purified Rat IgG2a Isotype Control (2A3)
Měrná jednotka: 1 * 100 µG
Image Unavailable-75-4321-U100

Rat IgG2a Isotype Control [clone: 2A3] (violetFluor® 450)

Katalogové číslo: (75-4321-U100)
Dodavatel: Tonbo Biosciences
Popis: The 2A3 immunoglobulin is useful as an isotype-matched control. The 2A3 immunolglobulin has an unknown binding specificity and is used as an isotype control for rat IgG2a antibodies.
Měrná jednotka: 1 * 100 µG
Product Image-75-1276-U100

Anti-Ly-6G Rat Monoclonal Antibody (violetFluor® 450) [clone: 1A8]

Katalogové číslo: (75-1276-U100)
Dodavatel: Tonbo Biosciences
Popis: The 1A8 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils.
Měrná jednotka: 1 * 100 µG
Product Image-70-0451-U100

Anti-PTPRC Rat Monoclonal Antibody [clone: 30-F11]

Katalogové číslo: (70-0451-U100)
Dodavatel: Tonbo Biosciences
Popis: The 30-F11 antibody reacts with mouse CD45, which is one of the most abundant hematopoietic markers and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB and CD45RO.
Měrná jednotka: 1 * 100 µG
Product Image-70-0453-U100

Anti-CD45.1 Mouse Monoclonal Antibody [clone: A20]

Katalogové číslo: (70-0453-U100)
Dodavatel: Tonbo Biosciences
Popis: The A20 antibody reacts with mouse CD45.1, also known as Ly5.1, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors.
Měrná jednotka: 1 * 100 µG
Image Unavailable-70-1522-U100

Anti-CTLA4 Armenian Hamster monoclonal antibody [clone: UC10-4F10-11]

Katalogové číslo: (70-1522-U100)
Dodavatel: Tonbo Biosciences
Popis: Anti-CTLA4 Armenian Hamster Monoclonal Antibody [clone: UC10-4F10-11]
Měrná jednotka: 1 * 100 µG
Product Image-50-1243-U100

Anti-CD274 Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: 10F.9G2]

Katalogové číslo: (50-1243-U100)
Dodavatel: Tonbo Biosciences
Popis: The 10F.9G2 antibody is specific for mouse CD274, more commonly known as PD-L1 or B7-H1, which acts as a ligand for the T cell co-regulatory receptor PD-1 (CD279). This interaction modulates T cell antigen receptor (TCR) signaling and therefore T cell activation. PD-L1 binding to PD-1 expressed on CD4- CD8- thymocytes participates in the processes of clonal selection, elimination of autoreactive lymphocytes, and development of tolerance. PD-L1 may also bind PD-1 following the receptor’s inducible expression on activated, mature T cells, where it has been proposed to limit T cell activation. PD-L1 is one of a group of “B7” ligands whose interactions with the CD28 receptor family, also including CTLA-4 (CD152), provide a balance of co-stimulatory /co-inhibitory signaling important in T cell activation, tolerance, and autoimmunity.
Měrná jednotka: 1 * 100 µG
Product Image-50-1886-U100

Anti-CD8A Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: 2.43]

Katalogové číslo: (50-1886-U100)
Dodavatel: Tonbo Biosciences
Popis: The 2.43 antibody reacts with the 32 to 34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation induced by binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck and facilitate intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death in tumor cells, as well as in cells infected by virus, bacteria or parasites.
Měrná jednotka: 1 * 100 µG
Product Image-70-0259-U100

Anti-IL2RA Mouse Monoclonal Antibody [clone: BC96]

Katalogové číslo: (70-0259-U100)
Dodavatel: Tonbo Biosciences
Popis: The BC96 antibody is specific for human CD25, a 55 kDa surface protein also known as the Interleukin-2 Receptor alpha chain, or IL-2R alpha. CD25 may bind IL-2 by itself, although with low affinity and without induction of cell signaling. CD25 is also expressed within a high-affinity complex, along with the IL-2R beta chain (CD122) and the common gamma chain (CD132), to form a signaling receptor complex. Signaling via CD25 may modulate Th17 and Treg cell differentiation, and has been shown to play a role in the function of dendritic cells.
Měrná jednotka: 1 * 100 µG
Product Image-70-0251-U100

Anti-IL2RA Rat Monoclonal Antibody [clone: PC61.5]

Katalogové číslo: (70-0251-U100)
Dodavatel: Tonbo Biosciences
Popis: The PC61.5 antibody is specific for mouse CD25, a 55 kDa surface protein also known as the Interleukin-2 Receptor alpha chain, or IL-2R alpha. CD25 may bind IL-2 by itself, although with low affinity and without induction of cell signaling. CD25 is also expressed within a high-affinity complex, along with the IL-2R beta chain (CD122) and the common gamma chain (CD132), to form a signaling receptor complex. Expression of CD25 varies during developmental stages of T and B cells, is induced on activated mature T and B cells, and is present on subsets of dendritic cells. CD25 signaling as part of the IL-2 receptor complex triggers T cell activation and proliferation, as well as modulating the differentiation and function of Th17 cells, T regulatory (Treg) cells, and dendritic cells.
Měrná jednotka: 1 * 100 µG
Product Image-60-1886-U100

Anti-CD8A Rat Monoclonal Antibody (PE (Phycoerythrin)/Cy7®) [clone: 2.43]

Katalogové číslo: (60-1886-U100)
Dodavatel: Tonbo Biosciences
Popis: The 2, 43 antibody reacts with the 32 to 34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation induced by binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck and facilitate intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death in tumor cells, as well as in cells infected by virus, bacteria or parasites.
Měrná jednotka: 1 * 100 µG
Image Unavailable-35-4031-U100

Rat IgG2b Isotype Control [clone: LTF-2] (FITC (Fluorescein Isothiocyanate))

Katalogové číslo: (35-4031-U100)
Dodavatel: Tonbo Biosciences
Popis: The LTF-2 immunoglobulin is useful as an isotype-matched control. The LTF-2 immunolglobulin has an unknown binding specificity and is used as an isotype control for rat IgG2b antibodies.
Měrná jednotka: 1 * 100 µG
Product Image-35-5874-U100

Anti-TNFRSF18 Rat Monoclonal Antibody (FITC (Fluorescein)) [clone: DTA-1]

Katalogové číslo: (35-5874-U100)
Dodavatel: Tonbo Biosciences
Popis: The DTA-1 antibody reacts with mouse CD357, also known as GITR or AITR (in humans), a 66-70 kDa member of the Tumor Necrosis Factor superfamily (TNFRSF18). GITR is primarily found on T cells, and its function may vary depending on the T cell type where it is expressed. GITR is upregulated on activated T cells where it provides co-stimulation, yet GITR may promote the inhibition of CD4+ CD25+ Treg cells, where it is expressed at high levels. GITR ligand (GITRL) is found on B cells, macrophages, dendritic and endothelial cells, and is implicated in regulating both innate and adaptive immune responses.
Měrná jednotka: 1 * 100 µG
Product Image-30-5931-U100

Anti-Ly-6G Rat Monoclonal Antibody (Biotin) [clone: RB6-8C5]

Katalogové číslo: (30-5931-U100)
Dodavatel: Tonbo Biosciences
Popis: The RB6-8C5 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils.
Měrná jednotka: 1 * 100 µG
Cena na vyžádání
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Omezené množství produktu na skladě. Zboží může být k dispozici v jiném skladě poblíž vašeho sídla. Přesvědčte se, že jste přihlášení na stránky, abyste mohli vidět dostupné položky na skladě. Pokud je stále zobrazeno call a potřebujete asistenci, volejte na číslo 321 570 321.
Daná chemikálie je regulována dle platné legislativy a bude vyžadováno vyplnění formuláře. Jeho včasným vyplněním uspíšíte dodání produktu.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Tento produkt je zablokován vaší organizací. Kontaktujte své nákupní oddělení pro více informací.
Původní produkt již není k dispozici. Zobrazen je náhradní produkt.
Tento produkt již není k dispozici. Podobné produkty můžete vyhledat pomocí VWR katalogových čísel nebo čísel dodavatele uvedených výše. Pokud potřebujete další asistenci, zavolejte na telefonní číslo zákaznického servisu VWR 321 570 321.
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