Popis: Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines. RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in patterns of 5-HT2C editing in depressed suicide victims. [provided by RefSeq, Jul 2008].

Katalogové číslo: BOSSBS-2959R-A555

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: MAb B-R18 specifically recognizes CD95, also known as Fas, a transmembrane glycoprotein with a MW of 40-45 kDa, containing 8 kDa of N-glycosidic-linked polysaccharide. It is a receptor for TNFSF6/FASLG, a member of the nerve growth factor receptor/tumor necrosis factor superfamily, mediating receptor-triggered apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation, which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). CD95 antigen is expressed on the surface of various cell types, preferentially on the CD45RAlow CD45ROhigh subset of memory T lymphocytes.

Katalogové číslo: BNC940305-100

Měrná jednotka: 1 * 100 µl

Dodavatel: Biotium

Akce

Popis: MAb B-R18 specifically recognizes CD95, also known as Fas, a transmembrane glycoprotein with a MW of 40-45 kDa, containing 8 kDa of N-glycosidic-linked polysaccharide. It is a receptor for TNFSF6/FASLG, a member of the nerve growth factor receptor/tumor necrosis factor superfamily, mediating receptor-triggered apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation, which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). CD95 antigen is expressed on the surface of various cell types, preferentially on the CD45RAlow CD45ROhigh subset of memory T lymphocytes.

Katalogové číslo: BNUM0305-50

Měrná jednotka: 1 * 50 µl

Dodavatel: Biotium

Akce

Popis: MAb B-R18 specifically recognizes CD95, also known as Fas, a transmembrane glycoprotein with a MW of 40-45 kDa, containing 8 kDa of N-glycosidic-linked polysaccharide. It is a receptor for TNFSF6/FASLG, a member of the nerve growth factor receptor/tumor necrosis factor superfamily, mediating receptor-triggered apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation, which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). CD95 antigen is expressed on the surface of various cell types, preferentially on the CD45RAlow CD45ROhigh subset of memory T lymphocytes.

Katalogové číslo: BNC040305-100

Měrná jednotka: 1 * 100 µl

Dodavatel: Biotium

Akce

Popis: Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.

Katalogové číslo: CAYM10007898-5

Měrná jednotka: 1 * 5 mg

Dodavatel: Cayman Chemical

Akce

Popis: L-Glucono-1,5-lactone ≥85%

Katalogové číslo: APOSBIG1121-250MG

Měrná jednotka: 1 * 250 mg

Dodavatel: Apollo Scientific

Akce

Popis: 2,3,5-Tri-O-acetyl-D-xylonic acid, γ-lactone ≥98%

Katalogové číslo: APOSBICL4287-1G

Měrná jednotka: 1 * 1 g

Dodavatel: Apollo Scientific

Akce

Popis: Appearance: White Powder or crystals

Katalogové číslo: ACRO204450250

Měrná jednotka: 1 * 25 g

Dodavatel: Thermo Fisher Scientific

Bezpečnostní list Akce

Popis: (-)-Corey lactone benzoate 98%

Katalogové číslo: APOSOR46255-1G

Měrná jednotka: 1 * 1 g

Dodavatel: Apollo Scientific

Akce

Popis: Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines. RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in patterns of 5-HT2C editing in depressed suicide victims. [provided by RefSeq, Jul 2008].

Katalogové číslo: BOSSBS-2959R-CY3

Měrná jednotka: 1 * 100 µl

Dodavatel: Bioss

Akce

Popis: MAb B-R18 specifically recognizes CD95, also known as Fas, a transmembrane glycoprotein with a MW of 40-45 kDa, containing 8 kDa of N-glycosidic-linked polysaccharide. It is a receptor for TNFSF6/FASLG, a member of the nerve growth factor receptor/tumor necrosis factor superfamily, mediating receptor-triggered apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation, which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). CD95 antigen is expressed on the surface of various cell types, preferentially on the CD45RAlow CD45ROhigh subset of memory T lymphocytes.

Katalogové číslo: BNUB0305-500

Měrná jednotka: 1 * 500 µl

Dodavatel: Biotium

Akce

Popis: 4-Hydroxy-1-cyclohexanecarboxylic acid-δ-lactone 98%

Katalogové číslo: APOSOR920857-5G

Měrná jednotka: 1 * 5 g

Dodavatel: Apollo Scientific

Akce

Popis: D-Glucofuranuronic acid, gamma-lactone-1,6-13C2 (99% ¹³C )

Katalogové číslo: APOSBICL4106-250MG

Měrná jednotka: 1 * 250 mg

Dodavatel: Apollo Scientific

Akce

Popis: 2,3-O-Isopropylidene-L-gulono-1,4-lactone ≥98%

Katalogové číslo: APOSBICL4123-1G

Měrná jednotka: 1 * 1 g

Dodavatel: Apollo Scientific

Akce

Popis: MAb B-R18 specifically recognizes CD95, also known as Fas, a transmembrane glycoprotein with a MW of 40-45 kDa, containing 8 kDa of N-glycosidic-linked polysaccharide. It is a receptor for TNFSF6/FASLG, a member of the nerve growth factor receptor/tumor necrosis factor superfamily, mediating receptor-triggered apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation, which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). CD95 antigen is expressed on the surface of various cell types, preferentially on the CD45RAlow CD45ROhigh subset of memory T lymphocytes.

Katalogové číslo: BNC470305-500

Měrná jednotka: 1 * 500 µl

Dodavatel: Biotium

Akce

Popis: (-)-Corey lactone-4-phenylbenzoate 98%

Katalogové číslo: APOSOR46130-5G

Měrná jednotka: 1 * 5 g

Dodavatel: Apollo Scientific

Akce