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Human recombinant plasma kallikrein (from cells)

Dodavatel: ProSci Inc.

92-422
PRSI92-422EA 18630 CZK
PRSI92-422
Human recombinant plasma kallikrein (from cells)
Proteiny

KLKB1 is a 638 amino acids protein that belongs to the peptidase S1 family and plasma kallikrein subfamily. It contains a peptidase S1 domain and four apple domains. The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. It participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation.Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.


Fusion-Tag: C-6 His tag


This recombinant protein can be used for biological assays. For research use only.

Objednat


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