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MPBH (4-(4-N-Maleimidophenyl)butyric acid hydrazide hydrochloride), Pierce™

Dodavatel: Thermo Fisher Scientific

Synonyms: MPBH

22305
PIER22305EA 14220 CZK
PIER22305
MPBH (4-(4-N-Maleimidophenyl)butyric acid hydrazide hydrochloride), Pierce™
MPBH (4-(4-N-Maleimidophenyl)butyric acid hydrazide hydrochloride)

Thermo Scientific Pierce MPBH is a long, maleimide-and-hydrazide crosslinker for conjugating sulfhydryls (cysteines) to carbonyls (aldehyde or ketones, such as those formed by oxidation of glycoprotein carbohydrates).


  • Reactive groups: maleimide and hydrazide
  • Reactive towards: sulfhydryl groups and carbonyl (aldehyde) groups
  • Long (17.9A), sulfhydryl-to-aldehyde crosslinker with an aromatic ring in its spacer arm (noncleavable)
  • Maleimide group reacts with sulfhydryl groups to form stable thioether linkages
  • Hydrazide group conjugates to oxidized sugars of glycoproteins and carbohydrates
  • Use sodium meta-periodate to oxidize glycosylation (e.g., sialic acid) to reactive aldehyde groups
  • Use with EDC to conjugate primary amine of hydrazide group to carboxyl groups


Related Products, BMPH, EMCH, KMUH


Upozornení: For Research Use Only. Not for use in diagnostic procedures.

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Výsledky specifikačního testu

Product Line Pierce™
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Reactive Moiety Amine, Hydrazide, Maleimide
Spacer Long
Form Powder
Quantity 50 mg
Type Crosslinker
Solubility DMF, DMSO

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