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Anti-XPC Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Dodavatel: Bioss
BS-6634R-FITC
BOSSBS-6634R-FITCEA 26060 CZK
BOSSBS-6634R-FITC
Anti-XPC Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
Protilátky
Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsicMore Product Information
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