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Anti-ATG7 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Dodavatel: Bioss
BS-2432R-A350
BOSSBS-2432R-A350EA 25660 CZK
BOSSBS-2432R-A350
Anti-ATG7 Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Protilátky
E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energyMore Product Information
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