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Anti-Gemin 2/SMA Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Dodavatel: Bioss
BS-11562R-A680
BOSSBS-11562R-A680EA 25340 CZK
BOSSBS-11562R-A680
Anti-Gemin 2/SMA Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Protilátky
Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterised by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (survival of motor neuron) gene. Gemin2 (formerly known as SIP1 for SMN interacting protein) associates directly with SMN and is a part of the SMN complex containing Gemin3 (a DEAD-box RNA helicase), Gemin4, Gemin5 and Gemin6, as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in splicesomal snRNP assembly in the cytoplasm and is required for pre-mRNAMore Product Information
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Produktová specifikace

Název antigenu Gemin 2/SMA
Environmentally Preferable
Synonyma antigenu SMN interacting protein 1|SIP1-delta |SMN interacting protein 1 delta|GEMI2_HUMAN|gemin2|SIP 1|Survival of motor neuron protein interacting protein 1|SMN-interacting protein 1|SIP1|Survival of motor neuron protein-interacting protein 1|Component of gems 2|Gemin2|SIP-1|SIP1 delta|Survival interacting protein 1|Gem nuclear organelle associated protein 2|Gemin-2|Gem associated protein 2
Druh protilátky Primární
Klonovalita Polyclonal
Spojení Alexa Fluor® 680
Reaktivita Human,Rat
Hostitel Rabbit
Izotyp IgG
Western blot Yes
Imunochemie Yes
ImunoFluorescence Yes
Modifikace Unmodified
Epitop 101-200/280
Imunogen KLH conjugated synthetic peptide derived from human Gemin 2
Formulář Liquid
Molekulární hmotnost 32 kDa
Čištění Purified by Protein A
Koncentrace 1 µg/µl
Skladovací pufr Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
Skladovací teplota Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Transportní teplota 4 °C
Testované aplikace ICC

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