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Anti-CD272 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Dodavatel: Bioss
BS-0624R-A750
BOSSBS-0624R-A750EA 25340 CZK
BOSSBS-0624R-A750
Anti-CD272 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Protilátky
B and T lymphocyte attenuator (BTLA), an immunoglobulin domain-containing glycoprotein with two immunoreceptor tyrosine-based inhibitory motifs. BTLA is not expressed by naive T cells, but it is induced during activation and remains expressed on T helper type 1 (T(H)1) but not T(H)2 cells. Crosslinking BTLA with antigen receptors induces its tyrosine phosphorylation and association with the Src homology domain 2 (SH2)-containing protein tyrosine phosphatases SHP-1 and SHP-2, and attenuates production of interleukin 2 (IL-2). BTLA-deficient T cells show increased proliferation, and BTLA-More Product Information
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