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Curcumin ≥99.5% (by HPLC) matrix substance for MALDI-MS, Supelco®

Dodavatel: Merck

78246-100MG
78246-100MGEA 7080 CZK
78246-100MG
Curcumin ≥99.5% (by HPLC) matrix substance for MALDI-MS, Supelco®
Curcumin

A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Curcumin has been cited as a potential chemopreventive agent, in addition to its chemotherapeutic activity. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.

Vzorec: C₂₁H₂₀O₆
Bod tání: 183…188 °C
Storage Temperature: Refrigerator
MDL Number: MFCD00008365
CAS číslo: 458-37-7

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Výsledky specifikačního testu

Appearance (Color) Yellow to Very Dark Yellow and Orange to Very Dark Orange
Appearance (Form) Powder or Crystals
Purity (HPLC area %) ≥ 99.5 %
Melting Point 183 - 188 C
Carbon Content 68.47 % (theory)
Hydrogen Content 5.47 % (theory)
Proton NMR Spectrum Conforms to structure
Metal trace Analysis (ICP) Corresponds to requirements
BARIUM (ICP) ≤ 5 mg/kg
CALCIUM (ICP) ≤ 100 mg/kg
CADMIUM (ICP) ≤ 5 mg/kg
COBALT (ICP) ≤ 5 mg/kg
CHROMIUM (ICP) ≤ 5 mg/kg
COPPER (ICP) ≤ 5 mg/kg
IRON (ICP) ≤ 30 mg/kg
POTASSIUM (ICP) ≤ 50 mg/kg
MAGNESIUM (ICP) ≤ 30 mg/kg
MANGANESE (ICP) ≤ 5 mg/kg
SODIUM (ICP) ≤ 50 mg/kg
NICKEL (ICP) ≤ 5 mg/kg
LEAD (ICP) ≤ 5 mg/kg
ZINC (ICP) ≤ 5 mg/kg
RECOMMENDED RETEST PERIOD 36 MONTHS


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